tert-Butyl (trans-4-(hydroxymethyl)cyclohexyl)carbamate
Based on 1 Customer Validation
tert-Butyl (trans-4-(hydroxymethyl)cyclohexyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.95%
- CAS No.: 239074-29-4
- Formula: C12H23NO3
- Molecular Weight:229.32
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E903 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 239074-29-4
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Appearance Solid
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Molecular Weight 229.32
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Formula C12H23NO3
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SMILES
N(C(OC(C)(C)C)=O)[C@@H]1CC[C@@H](CO)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (436.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (240 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3607 mL | 21.8036 mL | 43.6072 mL | 109.0180 mL |
| 5 mM | 0.8721 mL | 4.3607 mL | 8.7214 mL | 21.8036 mL | |
| 10 mM | 0.4361 mL | 2.1804 mL | 4.3607 mL | 10.9018 mL | |
| 15 mM | 0.2907 mL | 1.4536 mL | 2.9071 mL | 7.2679 mL | |
| 20 mM | 0.2180 mL | 1.0902 mL | 2.1804 mL | 5.4509 mL | |
| 25 mM | 0.1744 mL | 0.8721 mL | 1.7443 mL | 4.3607 mL | |
| 30 mM | 0.1454 mL | 0.7268 mL | 1.4536 mL | 3.6339 mL | |
| 40 mM | 0.1090 mL | 0.5451 mL | 1.0902 mL | 2.7254 mL | |
| 50 mM | 0.0872 mL | 0.4361 mL | 0.8721 mL | 2.1804 mL | |
| 60 mM | 0.0727 mL | 0.3634 mL | 0.7268 mL | 1.8170 mL | |
| 80 mM | 0.0545 mL | 0.2725 mL | 0.5451 mL | 1.3627 mL | |
| 100 mM | 0.0436 mL | 0.2180 mL | 0.4361 mL | 1.0902 mL |
tert-Butyl (trans-4-(hydroxymethyl)cyclohexyl)carbamate Related Classifications
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