Tetra-N-acetylchitotetraose
Based on 1 Customer Validation
Tetra-N-acetylchitotetraose is a linear chitosan oligosaccharide. Tetra-N-acetylchitotetraose is a component of the hpo-chitoo gosacchaπdes (LCOs) secreted from Rhizobia. Tetra-N-acetylchitotetraose is also a substrate for the Rhizobium leguminosarum nodulation protein NodB, a CO deacetylase.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 2706-65-2
- Formula: C32H54N4O21
- Molecular Weight:830.79
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-135072
N,N',N''-Triacetylchitotriose
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HY-130778
N,N'-Diacetylchitobiose
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HY-N7698A
Penta-N-acetylchitopentaose
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HY-N1132
D-(+)-Trehalose
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HY-CP001
D-Trehalose, Carrier Protein
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HY-135072R
N,N',N''-Triacetylchitotriose (Standard)
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HY-N1132R
D-(+)-Trehalose (Standard)
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HY-B2144A
Chitosan (MW 150000) (≥85% deacetylated)
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HY-B1779
Sucrose
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HY-B2144B
Chitosan (MW 30000) (≥85% deacetylated)
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HY-B2144K
Chitosan (≥85% deacetylated, viscosity>90 mPa.s, MW 15000)
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HY-N7697B
Chitobiose dihydrochloride
Biological Activity
Tetra-N-acetylchitotetraose inhibits the lytic activity of hen egg white lysozyme toward Micrococcus lysodeikticus cells with an IC50 of 7.7 μM[1].
Tetra-N-acetylchitotetraose can be deacetylated by chitin deacetylase from Mucor rouxii[2].
Tetra-N-acetylchitotetraose acts as a substrate for recombinant maize chitinase-A enzymatic hydrolysis[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2706-65-2
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Appearance Solid
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Molecular Weight 830.79
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Formula C32H54N4O21
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Color White to off-white
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SMILES
CC(N[C@H]([C@H]([C@@H]1O[C@H](O[C@@H]2CO)[C@@H]([C@H]([C@@H]2O)O)NC(C)=O)O)[C@@H](O[C@@H]1CO)O[C@@H]([C@@H]([C@H]3NC(C)=O)O)[C@H](O[C@H]3O[C@H]([C@H](O)CO)[C@H](O)[C@H](C=O)NC(C)=O)CO)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 100 mg/mL (120.37 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Ogata M, et al. A novel transition-state analogue for lysozyme, 4-O-β-tri-N-acetylchitotriosyl moranoline, provided evidence supporting the covalent glycosyl-enzyme intermediate. J Biol Chem. 2013 Mar 1;288(9):6072-82. [Content Brief]
[2]. Tsigos I, et al. Mode of action of chitin deacetylase from Mucor rouxii on N-acetylchitooligosaccharides. Eur J Biochem. 1999;261(3):698-705. [Content Brief]
[3]. Singh S, et al. Glycosidase-catalysed oligosaccharide synthesis: preparation of N-acetylchitooligosaccharides using the beta-N-acetylhexosaminidase of Aspergillus oryzae. Carbohydr Res. 1995;279:293-305. [Content Brief]
[4]. Volpicella M, et al. Characterization of maize chitinase-A, a tough allergenic molecule. Allergy. 2017;72(9):1423-1429. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.2037 mL | 6.0184 mL | 12.0367 mL | 30.0918 mL |
| 5 mM | 0.2407 mL | 1.2037 mL | 2.4073 mL | 6.0184 mL | |
| 10 mM | 0.1204 mL | 0.6018 mL | 1.2037 mL | 3.0092 mL | |
| 15 mM | 0.0802 mL | 0.4012 mL | 0.8024 mL | 2.0061 mL | |
| 20 mM | 0.0602 mL | 0.3009 mL | 0.6018 mL | 1.5046 mL | |
| 25 mM | 0.0481 mL | 0.2407 mL | 0.4815 mL | 1.2037 mL | |
| 30 mM | 0.0401 mL | 0.2006 mL | 0.4012 mL | 1.0031 mL | |
| 40 mM | 0.0301 mL | 0.1505 mL | 0.3009 mL | 0.7523 mL | |
| 50 mM | 0.0241 mL | 0.1204 mL | 0.2407 mL | 0.6018 mL | |
| 60 mM | 0.0201 mL | 0.1003 mL | 0.2006 mL | 0.5015 mL | |
| 80 mM | 0.0150 mL | 0.0752 mL | 0.1505 mL | 0.3761 mL | |
| 100 mM | 0.0120 mL | 0.0602 mL | 0.1204 mL | 0.3009 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Tetra-N-acetylchitotetraose Related Classifications
HY-N7698 Related Classifications
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