Thalidomide-5-NH-PEG2-NH2 hydrochloride
Based on 1 Customer Validation
Thalidomide-5-NH-PEG2-NH2 hydrochloride is a Thalidomide (HY-14658)-based cereblon ligand that recruits CRBN proteins. Thalidomide-5-NH-PEG2-NH2 hydrochloride can be connected to the target protein ligand through a linker to form a PROTAC molecule. For example, THAL-SNS-032 (HY-123937).
For research use only. We do not sell to patients.
- CAS No.: 2357110-58-6
- Formula: C19H25ClN4O6
- Molecular Weight:440.88
-
Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All E3 Ligase Ligand-Linker Conjugates Isoforms
More
Biological Activity
|
Cereblon |
Chemical Information
-
CAS No. 2357110-58-6
-
Appearance Solid
-
Molecular Weight 440.88
-
Formula C19H25ClN4O6
-
Color Light yellow to brown
-
SMILES
O=C1NC(C(CC1)N2C(C3=CC=C(NCCOCCOCCN)C=C3C2=O)=O)=O.Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
-
Data Sheet (264 KB)
-
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)