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Topoisomerase II α, Human

Topoisomerase II α, Human (EC 5.99.1.3) is a nuclear enzyme that play essential roles in DNA replication, transcription, chromosome segregation, and recombination. All cells have two major forms of topoisomerases: type I, which makes single-stranded cuts in DNA, and type II enzymes, which cut and pass double-stranded DNA.

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  • Topoisomerase II α, Human Chemical Structure
    Topoisomerase II α, Human Chemical Structure
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All Topoisomerase Isoforms

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  • Topoisomerase II α, Human