Tubulin polymerization-IN-22
Tubulin polymerization-IN-22 is a tubulin polymerization inhibitor with an IC50 of 8.1 μM. Tubulin polymerization-IN-22 arrests cell cycle at G2/M phase and induces apoptosis.
For research use only. We do not sell to patients.
- CAS No.: 2493052-22-3
- Formula: C19H16O4
- Molecular Weight:308.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Tubulin polymerization-IN-22 (Compound 4u) shows antiproliferative activity against human breast cancer cell line (MCF-7) with an IC50 of 1.47 μM[1].
Tubulin polymerization-IN-22 (Compound 4u) is a tubulin polymerization inhibitor by targeting the Colchicine binding site[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2493052-22-3
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Molecular Weight 308.33
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Formula C19H16O4
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SMILES
O=C(C1=CC=C(OC)C(O)=C1)C2=C3C=CC=CC3=C(OC)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)