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Cat. No.: HY-145868

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Tubulin polymerization-IN-3

Tubulin polymerization-IN-3 (compound 4c) is a potent tubulin polymerization inhibitor, with an IC₅₀ of 3.84 µM. Tubulin polymerization-IN-3 can induce apoptosis in colon cancer cells.

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Formule: C₂₀H₂₀ClN₅O₃
Masse moléculaire:413.86

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Tubulin polymerization-IN-3 Chemical Structure

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Quantité

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Tubulin polymerization-IN-3 (compound 4c) is a potent tubulin polymerization inhibitor, with an IC₅₀ of 3.84 µM. Tubulin polymerization-IN-3 can induce apoptosis in colon cancer cells^[1].

Chemical Information

Masse moléculaire 413.86
Formule C₂₀H₂₀ClN₅O₃
SMILES

COC1=CC(C2=CC(C3C=CC(Cl)=CC3)=NC4=NC(N)=NN24)=CC(OC)=C1OC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Mohamed HS, et, al. Design, synthesis, biological assessment, and in-Silico studies of 1,2,4-triazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors. Bioorg Chem. 2022 Apr;121:105687. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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