PLpro-IN-7
PLpro-IN-7 (compund 83) is a novel papain-like protease (PLpro) inhibitor with IC50 of 3 nM.
For research use only. We do not sell to patients.
- CAS No.: 3046158-99-7
- Formula: C30H34ClN7O
- Molecular Weight:544.09
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
PLpro[1]
Chemical Information
-
CAS No. 3046158-99-7
-
Molecular Weight 544.09
-
Formula C30H34ClN7O
-
SMILES
CC1=CC=C(C=C1C(N[C@@H](C2=CC(C3=C(N=CC(Cl)=C3)N)=CC(C4=CN(N=C4)C)=C2)C)=O)N5CCN(CC5)C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
[1]. WO2024121709A1
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)