Bisbentiamine
Based on 1 Customer Validation
Bisbentiamine is a lipophilic thiamine prodrug with pH-dependent solubility. The bioavailability of Bisbentiamine is regulated by diet type, administration time, gastric acidity, and formulation.
For research use only. We do not sell to patients.
- Purity: 99.52%
- CAS No.: 2667-89-2
- Formula: C38H42N8O6S2
- Molecular Weight:770.92
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Bisbentiamine exhibits pH-dependent solubility: it dissolves readily in acidic environments but is poorly soluble in neutral pH conditions, and is classified as a dissolution rate-controlled compound[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2667-89-2
-
Appearance Solid
-
Molecular Weight 770.92
-
Formula C38H42N8O6S2
-
Color White to off-white
-
SMILES
O=CN(CC1=CN=C(C)N=C1N)/C(C)=C(SS/C(CCOC(C2=CC=CC=C2)=O)=C(N(CC3=CN=C(C)N=C3N)C=O)/C)/CCOC(C4=CC=CC=C4)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (129.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (273 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2972 mL | 6.4858 mL | 12.9715 mL | 32.4288 mL |
| 5 mM | 0.2594 mL | 1.2972 mL | 2.5943 mL | 6.4858 mL | |
| 10 mM | 0.1297 mL | 0.6486 mL | 1.2972 mL | 3.2429 mL | |
| 15 mM | 0.0865 mL | 0.4324 mL | 0.8648 mL | 2.1619 mL | |
| 20 mM | 0.0649 mL | 0.3243 mL | 0.6486 mL | 1.6214 mL | |
| 25 mM | 0.0519 mL | 0.2594 mL | 0.5189 mL | 1.2972 mL | |
| 30 mM | 0.0432 mL | 0.2162 mL | 0.4324 mL | 1.0810 mL | |
| 40 mM | 0.0324 mL | 0.1621 mL | 0.3243 mL | 0.8107 mL | |
| 50 mM | 0.0259 mL | 0.1297 mL | 0.2594 mL | 0.6486 mL | |
| 60 mM | 0.0216 mL | 0.1081 mL | 0.2162 mL | 0.5405 mL | |
| 80 mM | 0.0162 mL | 0.0811 mL | 0.1621 mL | 0.4054 mL | |
| 100 mM | 0.0130 mL | 0.0649 mL | 0.1297 mL | 0.3243 mL |