2. Apoptosis
  3. Apoptosis
  4. Vin-C01

Vin-C01 is a potent pancreatic β-cells protective agent with an EC50 of 0.22 μM. Vin-C01 effectively promotes β-cell survival and protects β-cells from STZ (HY-13753)-induced apoptosis. Vin-C01 can be used for type 2 diabetes mellitus research.

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Vin-C01

Vin-C01 화학구조

CAS No. : 23173-26-4

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Vin-C01 Related Antibodies

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제품 설명

Vin-C01 is a potent pancreatic β-cells protective agent with an EC50 of 0.22 μM. Vin-C01 effectively promotes β-cell survival and protects β-cells from STZ (HY-13753)-induced apoptosis. Vin-C01 can be used for type 2 diabetes mellitus research[1].

IC50 & Target

EC50: 0.22 µM (pancreatic β-cells)[1]
Cellular Effect
Cell Line Type Value Description References
INS1(832/13) EC50
0.22 μM
Compound: Vin-C01
Cytoprotective activity in rat INS-1 832/13 cells assessed as inhibition of STZ-induced apoptosis incubated for 24 hrs by MTT assay
Cytoprotective activity in rat INS-1 832/13 cells assessed as inhibition of STZ-induced apoptosis incubated for 24 hrs by MTT assay
[PMID: 31918073]
분자량

308.42

화학식

C20H24N2O
CAS No.
SMILES

[H][C@]12C3=C4CCN1CCC[C@]2(C=C(N3C5=CC=CC=C54)CO)CC
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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Vin-C01 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vin-C0123173-26-4Apoptosistype 2 diabetes mellituspancreatic β-cellsInhibitorinhibitorinhibit

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상품명:
Vin-C01
Cat. No.:
HY-147502
수량:
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