Xanthine oxidoreductase-IN-3
Xanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 26.3 nM. Xanthine oxidoreductase-IN-3 can be used for the research of acute hyperuricemia.
For research use only. We do not sell to patients.
- CAS No.: 651769-78-7
- Formula: C14H10ClN5O
- Molecular Weight:299.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 26.3 nM (xanthine oxidoreductase)[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:ICR mice (18-22 g) were induced acute hyperuricemia by injection of potassium oxonate and hypoxanthine[1]
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Dosage:5 mg/kg
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Administration:Suspended in 0.5% CMC-Na solution for intragastric administration
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Result:Showed a uric acid-lowering effect from 3 h after administration.
Chemical Information
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CAS No. 651769-78-7
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Molecular Weight 299.72
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Formula C14H10ClN5O
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SMILES
O=C(C1=CC=C(C=C1)C2=NN=NN2)NC3=CC=C(C=C3)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)