XMT-1519 conjugate-1
Based on 1 Customer Validation
XMT-1519 conjugate-1 (compound 31) is part of the drug-linker conjugate for ADC and can be conjugated with the HER-2 monoclonal antibody Calotatug (XMT-1519) (HY-P990909) for the synthesis of ADC.
For research use only. We do not sell to patients.
- Purity: 98.07%
- CAS No.: 2720500-19-4
- Formula: C101H149N23O42
- Molecular Weight:2357.39
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Storage:
-80°C
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2720500-19-4
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Appearance Solid
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Molecular Weight 2357.39
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Formula C101H149N23O42
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Color White to light yellow
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SMILES
O=C(C1=C(N=C(O1)C)CC)NC2=NC3=CC(C(N)=O)=CN=C3N2C/C=C/CN4C5=C(OCCCOC([C@H](C)NC(CCOCCOCCNC(CC[C@@H](C(NCC(NCC(NCC(NCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)=O)=O)=O)=O)=O)=O)NC(CN6C(C=CC6=O)=O)=O)=O)=O)=O)C=C(C(N)=O)C=C5N=C4NC(C7=C(N=C(O7)C)CC)=O
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Shipping
Shipping with dry ice.
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Storage
-80°C
Solvent & Solubility
DMSO : 100 mg/mL (42.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.4242 mL | 2.1210 mL | 4.2420 mL | 10.6049 mL |
| 5 mM | 0.0848 mL | 0.4242 mL | 0.8484 mL | 2.1210 mL | |
| 10 mM | 0.0424 mL | 0.2121 mL | 0.4242 mL | 1.0605 mL | |
| 15 mM | 0.0283 mL | 0.1414 mL | 0.2828 mL | 0.7070 mL | |
| 20 mM | 0.0212 mL | 0.1060 mL | 0.2121 mL | 0.5302 mL | |
| 25 mM | 0.0170 mL | 0.0848 mL | 0.1697 mL | 0.4242 mL | |
| 30 mM | 0.0141 mL | 0.0707 mL | 0.1414 mL | 0.3535 mL | |
| 40 mM | 0.0106 mL | 0.0530 mL | 0.1060 mL | 0.2651 mL |