2. Antibody-drug Conjugate/ADC Related
  3. Drug-Linker Conjugates for ADC
  4. XMT-1519 conjugate-1

ΧΜΤ-1519 conjugate-1 (compound 31) is a linker for the HER-2 monoclonal antibody XMT-1519, which can be used to synthesize ADC and increase anti-tumor activity.

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XMT-1519 conjugate-1 Chemical Structure

XMT-1519 conjugate-1 Chemical Structure

CAS No. : 2720500-19-4

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Based on 1 publication(s) in Google Scholar

XMT-1519 conjugate-1 Related Antibodies

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Description

ΧΜΤ-1519 conjugate-1 (compound 31) is a linker for the HER-2 monoclonal antibody XMT-1519, which can be used to synthesize ADC and increase anti-tumor activity[1].

Molecular Weight

2357.39

Formula

C101H149N23O42
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=C(N=C(O1)C)CC)NC2=NC3=CC(C(N)=O)=CN=C3N2C/C=C/CN4C5=C(OCCCOC([C@H](C)NC(CCOCCOCCNC(CC[C@@H](C(NCC(NCC(NCC(NCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)=O)=O)=O)=O)=O)=O)NC(CN6C(C=CC6=O)=O)=O)=O)=O)=O)C=C(C(N)=O)C=C5N=C4NC(C7=C(N=C(O7)C)CC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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XMT-1519 conjugate-1 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

XMT-1519 conjugate-12720500-19-4Drug-Linker Conjugates for ADCXMT-1519ADCanti-tumorInhibitorinhibitorinhibit

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