XMT-1519 conjugate-1

Name: XMT-1519 conjugate-1
Brand: MedChemExpress
SKU: HY-148067
Rating: 4.5 (0 reviews)

Cat. No.: HY-148067 Pureza: 98.07%: Ficha de datos
COA

SDS
Instrucciones de manejo
FAQs
Technical Support

XMT-1519 conjugate-1 (compound 31) is part of the drug-linker conjugate for ADC and can be conjugated with the HER-2 monoclonal antibody Calotatug (XMT-1519) (HY-P990909) for the synthesis of ADC.

Para uso exclusivo en investigación. No vendemos a pacientes.

XMT-1519 conjugate-1 Estructura química

No. CAS : 2720500-19-4

Tamaño	Stock	Cantidad
1 mg	En stock	Estimated Time of Arrival: December 31
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
200 mg	Obtener un presupuesto
500 mg	Obtener un presupuesto

or Consulta para venta a granel

* Seleccione Cantidad antes de agregar artículos.

This product is a controlled substance and not for sale in your territory.

Revisión del cliente

Based on 1 Customer Validation

Recomendaciones destacadas

•Related Small Molecules:

•Related Proteins:

Ver todos los productos específicos de isoformas Drug-Linker Conjugates for ADC:

Ver todas las isoformas

Auristatin Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents Dual payloads

Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

2357.39

Fòrmula

C₁₀₁H₁₄₉N₂₃O₄₂

No. CAS

2720500-19-4

Appearance

Solid

Color

White to light yellow

SMILES

O=C(C1=C(N=C(O1)C)CC)NC2=NC3=CC(C(N)=O)=CN=C3N2C/C=C/CN4C5=C(OCCCOC([C@H](C)NC(CCOCCOCCNC(CC[C@@H](C(NCC(NCC(NCC(NCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)=O)=O)=O)=O)=O)=O)NC(CN6C(C=CC6=O)=O)=O)=O)=O)=O)C=C(C(N)=O)C=C5N=C4NC(C7=C(N=C(O7)C)CC)=O

Envío

Shipping with dry ice.

Almacenamiento

-80°C

Solvente y solubilidad

In Vitro:

DMSO : 100 mg/mL (42.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.4242 mL	2.1210 mL	4.2420 mL
5 mM	0.0848 mL	0.4242 mL	0.8484 mL
10 mM	0.0424 mL	0.2121 mL	0.4242 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Pureza y Documentación

Purity: 99.26%

Select Batch:

Ficha de datos (276 KB) SDS (251 KB)

COA (261 KB) HNMR (534 KB) LCMS (95 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Jeremy R. Duvall, et al. Antibody drug conjugates comprising sting agonists. WO2021202984 A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.4242 mL	2.1210 mL	4.2420 mL	10.6049 mL
	5 mM	0.0848 mL	0.4242 mL	0.8484 mL	2.1210 mL
	10 mM	0.0424 mL	0.2121 mL	0.4242 mL	1.0605 mL
	15 mM	0.0283 mL	0.1414 mL	0.2828 mL	0.7070 mL
	20 mM	0.0212 mL	0.1060 mL	0.2121 mL	0.5302 mL
	25 mM	0.0170 mL	0.0848 mL	0.1697 mL	0.4242 mL
	30 mM	0.0141 mL	0.0707 mL	0.1414 mL	0.3535 mL
	40 mM	0.0106 mL	0.0530 mL	0.1060 mL	0.2651 mL