α-Glucosidase-IN-20
α-Glucosidase-IN-20 (Compound 3B) is a potent, orally active α-glucosidase inhibitor with an IC50 of 3.01 μM. α-Glucosidase-IN-20 shows anti-diabetic activity.
For research use only. We do not sell to patients.
- CAS No.: 420809-56-9
- Formula: C23H21NOS
- Molecular Weight:359.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
α-Glucosidase-IN-20 (10 and 20 mg/kg; p.o.; once) significantly decreases the serum glucose level after the administration of glucose (3 g/kg, oral) in rats[1].
α-Glucosidase-IN-20 (2000 mg/kg; p.o.; daily, for 2 weeks) demonstrates no mortality in mice[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Wistar albino rats (170-200 g), Streptozotocin-induced diabetes model[1]
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Dosage:10 and 20 mg/kg
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Administration:Oral administration; daily, for 4 weeks
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Result:Decreased the level of blood glucose, reversed Streptozocin-induced body weight loss. Showed antihyperlipidemic effects on Streptozotocin-induced diabetes, reduced to a significant level of serum biomarkers.
Chemical Information
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CAS No. 420809-56-9
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Molecular Weight 359.48
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Formula C23H21NOS
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SMILES
COC1=CC=C(C=C1)C2CC(C3=CC=C(C=C3)C)=NC4=C(S2)C=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
α-Glucosidase-IN-20 Related Classifications
HY-151144 Related Classifications
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