α-Lipoic Acid sodium (Standard)
α-Lipoic Acid (sodium) (Standard) is the analytical standard of α-Lipoic Acid (sodium). This product is intended for research and analytical applications. α-Lipoic Acid (Thioctic acid) sodium is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid sodium inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid sodium induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells. α-Lipoic Acid sodium can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2319-84-8
- 分子式: C8H13NaO2S2
- 分子量:228.31
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Product Information
-
化学情報
- 純度とドキュメンテーション
-
Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
-
CAS 番号 2319-84-8
-
分子量 228.31
-
分子式 C8H13NaO2S2
-
SMILES
O=C(O[Na])CCCCC1SSCC1
-
別名
Thioctic acid sodium (Standard); (±)-α-Lipoic acid sodium (Standard); DL-α-Lipoic acid sodium (Standard)
-
Structure Classification
-
Initial Source
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Xiao L, et al. Activity of the dietary antioxidant ergothioneine in a virus gene-based assay for inhibitors of HIV transcription. Biofactors. 2006;27(1-4):157-65. [Content Brief]
[2]. Lei D, et al. Synergistic neuroprotective effect of rasagiline and idebenone against retinal ischemia-reperfusion injury via the Lin28-let-7-Dicer pathway. Oncotarget. 2018 Jan 30;9(15):12137-12153. [Content Brief]
[3]. Yang Y, et al. Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway. J Nutr Biochem. 2014 Nov;25(11):1207-1217. [Content Brief]
[4]. Pibiri M, et al. α-Lipoic acid induces Endoplasmic Reticulum stress-mediated apoptosis in hepatoma cells. Sci Rep. 2020 Apr 28;10(1):7139. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
α-Lipoic Acid sodium (Standard) 関連分類
製品番号: HY-N0492AR
Powered by Bioz
- α-Lipoic Acid sodium (Standard)
- 2319-84-8
- Thioctic acid sodium (Standard)
- (±)-α-Lipoic acid sodium (Standard)
- DL-α-Lipoic acid sodium (Standard)
- Reference Standards
- NF-κB
- HIV
- Mitochondrial Metabolism
- Endogenous Metabolite
- Apoptosis
- antioxidant
- cofactor
- mitochondrial
- HIV-1
- LTR
- endoplasmic
- reticulum
- stress
- apoptosis
- hepatoma
- Inhibitor
- inhibitor
- inhibit