α-Glucosidase, Yeast
Based on 1 publication(s) in Google Scholar
α-Glucosidase, Yeast (α-D-Glucosidase, Yeast), a carbohydrate hydrolyzing enzyme, catalyzes the liberation of α-glucose from the non-reducing end of the substrate. α-Glucosidase can facilitate the absorption of glucose by the small intestine. Inhibition of α-Glucosidase is an effective management of non-insulin-dependent diabetes mellitus (NIDDM).
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- CAS No.: 9001-42-7
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) α-Glucosidase, Yeast
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Activité biologique
Description
In Vitro
Product information
Molecular weight: 68.5 kDa
Isoelectric point (pI): 5.9
Optimum pH: 6.5-7.5
Optimum reaction temperature: 37°C
pH stability: 6.0-8.5 (25°C, 24 hours)
Inhibitors: histidine, amines (Tris), metal ions (Hg2+, Cu2+, Ag+, Pb2+, Fe2+ and Zn2+), iodoacetate, 4-chloromercury benzoate.
Instructions
Dissolved in water at 1 mg/mL, divided into portions according to the single use amount and frozen at -20°C to avoid repeated freezing and thawing, and can be stored for up to 1 month. It can also be dissolved according to the specific experimental reference buffer.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
EC Number
3.2.1.20
Enzyme Activity
≥10 U/mg soild
Unit Definition
One unit is defined as the amount of enzyme that will convert 1 μmol PNPG to PNP per minute at 37°C and pH 7.0.
Chemical Information
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CAS No. 9001-42-7
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Appearance Solid
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Color White to off-white
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SMILES
[a-Glucosidase, Yeast]
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Synonyms
α-D-Glucosidase, Yeast
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
Solvant et solubilité
In Vitro:
H2O : 10 mg/mL (Need ultrasonic)
Pureté et documentation
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Fiche technique (270 KB)
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Kumar S, et, al. α-glucosidase inhibitors from plants: A natural approach to treat diabetes. Pharmacogn Rev. 2011 Jan;5(9):19-29. [Content Brief]
[2]. Laar FA, et, al. Alpha-glucosidase inhibitors for patients with type 2 diabetes: results from a Cochrane systematic review and meta-analysis. Diabetes Care. 2005 Jan;28(1):154-63. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)