2-Chloro-9-(beta-D-ribofuranosyl)purine
Based on 1 Customer Validation
2-Chloro-9-(beta-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity : 97.14%
- CAS No.: 5466-11-5
- Formula: C10H11ClN4O4
- Molecular Weight:286.67
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
Chemical Information
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CAS No. 5466-11-5
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Appearance Solid
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Molecular Weight 286.67
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Formula C10H11ClN4O4
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Color White to off-white
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SMILES
ClC(N=C1)=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (348.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4883 mL | 17.4417 mL | 34.8833 mL | 87.2083 mL |
| 5 mM | 0.6977 mL | 3.4883 mL | 6.9767 mL | 17.4417 mL | |
| 10 mM | 0.3488 mL | 1.7442 mL | 3.4883 mL | 8.7208 mL | |
| 15 mM | 0.2326 mL | 1.1628 mL | 2.3256 mL | 5.8139 mL | |
| 20 mM | 0.1744 mL | 0.8721 mL | 1.7442 mL | 4.3604 mL | |
| 25 mM | 0.1395 mL | 0.6977 mL | 1.3953 mL | 3.4883 mL | |
| 30 mM | 0.1163 mL | 0.5814 mL | 1.1628 mL | 2.9069 mL | |
| 40 mM | 0.0872 mL | 0.4360 mL | 0.8721 mL | 2.1802 mL | |
| 50 mM | 0.0698 mL | 0.3488 mL | 0.6977 mL | 1.7442 mL | |
| 60 mM | 0.0581 mL | 0.2907 mL | 0.5814 mL | 1.4535 mL | |
| 80 mM | 0.0436 mL | 0.2180 mL | 0.4360 mL | 1.0901 mL | |
| 100 mM | 0.0349 mL | 0.1744 mL | 0.3488 mL | 0.8721 mL |