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  2. Nucleoside Antimetabolite/Analog
  3. 2-Chloro-9-(beta-D-ribofuranosyl)purine

2-Chloro-9-(beta-D-ribofuranosyl)purine 

Cat. No.: HY-154516 Purity: 97.14%
Handling Instructions Technical Support

2-Chloro-9-(beta-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

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2-Chloro-9-(beta-D-ribofuranosyl)purine

2-Chloro-9-(beta-D-ribofuranosyl)purine 화학구조

CAS No. : 5466-11-5

사이즈 가격 재고 수량
1 mg 해외재고보유
5 mg 해외재고보유
10 mg 해외재고보유
50 mg   견적 받기  
100 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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제품 설명

2-Chloro-9-(beta-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

분자량

286.67

화학식

C10H11ClN4O4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC(N=C1)=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O

선적

Room temperature in continental US; may vary elsewhere.

보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 100 mg/mL (348.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4883 mL 17.4417 mL 34.8833 mL
5 mM 0.6977 mL 3.4883 mL 6.9767 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4883 mL 17.4417 mL 34.8833 mL 87.2083 mL
5 mM 0.6977 mL 3.4883 mL 6.9767 mL 17.4417 mL
10 mM 0.3488 mL 1.7442 mL 3.4883 mL 8.7208 mL
15 mM 0.2326 mL 1.1628 mL 2.3256 mL 5.8139 mL
20 mM 0.1744 mL 0.8721 mL 1.7442 mL 4.3604 mL
25 mM 0.1395 mL 0.6977 mL 1.3953 mL 3.4883 mL
30 mM 0.1163 mL 0.5814 mL 1.1628 mL 2.9069 mL
40 mM 0.0872 mL 0.4360 mL 0.8721 mL 2.1802 mL
50 mM 0.0698 mL 0.3488 mL 0.6977 mL 1.7442 mL
60 mM 0.0581 mL 0.2907 mL 0.5814 mL 1.4535 mL
80 mM 0.0436 mL 0.2180 mL 0.4360 mL 1.0901 mL
100 mM 0.0349 mL 0.1744 mL 0.3488 mL 0.8721 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
2-Chloro-9-(beta-D-ribofuranosyl)purine
Cat. No.:
HY-154516
수량:
MCE Japan Authorized Agent: