2-Chloro-9-(beta-D-ribofuranosyl)purine

Cat. No.: HY-154516 Purity: 97.14%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

2-Chloro-9-(beta-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

2-Chloro-9-(beta-D-ribofuranosyl)purine Chemical Structure

CAS No. : 5466-11-5

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Purity & Documentation
References
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Description

Molecular Weight

286.67

Formula

C₁₀H₁₁ClN₄O₄

CAS No.

5466-11-5

Appearance

Solid

Color

White to off-white

SMILES

ClC(N=C1)=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (348.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.4883 mL	17.4417 mL	34.8833 mL
5 mM	0.6977 mL	3.4883 mL	6.9767 mL
10 mM	0.3488 mL	1.7442 mL	3.4883 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 97.14%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (251 KB) HNMR (253 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.4883 mL	17.4417 mL	34.8833 mL	87.2083 mL
	5 mM	0.6977 mL	3.4883 mL	6.9767 mL	17.4417 mL
	10 mM	0.3488 mL	1.7442 mL	3.4883 mL	8.7208 mL
	15 mM	0.2326 mL	1.1628 mL	2.3256 mL	5.8139 mL
	20 mM	0.1744 mL	0.8721 mL	1.7442 mL	4.3604 mL
	25 mM	0.1395 mL	0.6977 mL	1.3953 mL	3.4883 mL
	30 mM	0.1163 mL	0.5814 mL	1.1628 mL	2.9069 mL
	40 mM	0.0872 mL	0.4360 mL	0.8721 mL	2.1802 mL
	50 mM	0.0698 mL	0.3488 mL	0.6977 mL	1.7442 mL
	60 mM	0.0581 mL	0.2907 mL	0.5814 mL	1.4535 mL
	80 mM	0.0436 mL	0.2180 mL	0.4360 mL	1.0901 mL
	100 mM	0.0349 mL	0.1744 mL	0.3488 mL	0.8721 mL