2-MSP-VA-PAB-MMAE
2-MSP-VA-PAB-MMAE (Compound B-2) is a conjugate of the toxin molecule MMAE (HY-15162) and a linker, which can be used to construct antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 99.65%
- CAS No.: 2878440-81-2
- Formula: C66H98N10O14S
- Molecular Weight:1287.61
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Chemical Information
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CAS No. 2878440-81-2
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Appearance Solid
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Molecular Weight 1287.61
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Formula C66H98N10O14S
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Color White to off-white
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SMILES
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](C)NC([C@H](C(C)C)NC(CCCC#CC4=CN=C(S(C)(=O)=O)N=C4)=O)=O)=O)=O)=O)=O)=O)OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (77.66 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 0.7766 mL | 3.8832 mL | 7.7663 mL | 19.4158 mL |
| 5 mM | 0.1553 mL | 0.7766 mL | 1.5533 mL | 3.8832 mL | |
| 10 mM | 0.0777 mL | 0.3883 mL | 0.7766 mL | 1.9416 mL | |
| 15 mM | 0.0518 mL | 0.2589 mL | 0.5178 mL | 1.2944 mL | |
| 20 mM | 0.0388 mL | 0.1942 mL | 0.3883 mL | 0.9708 mL | |
| 25 mM | 0.0311 mL | 0.1553 mL | 0.3107 mL | 0.7766 mL | |
| 30 mM | 0.0259 mL | 0.1294 mL | 0.2589 mL | 0.6472 mL | |
| 40 mM | 0.0194 mL | 0.0971 mL | 0.1942 mL | 0.4854 mL | |
| 50 mM | 0.0155 mL | 0.0777 mL | 0.1553 mL | 0.3883 mL | |
| 60 mM | 0.0129 mL | 0.0647 mL | 0.1294 mL | 0.3236 mL |
2-MSP-VA-PAB-MMAE Related Classifications
HY-187075 Related Classifications
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