20(R)-25-Methoxyprotopanaxadiol
20(R)-25-Methoxyprotopanaxadiol (20(R)-25-OCH3-PPD) is a dammarane-type triterpene sapogenin found in Panax ginseng berries. 20(R)-25-Methoxyprotopanaxadiol induces cytotoxicity in cancer cells. 20(R)-25-Methoxyprotopanaxadiol can be used for the research of lung cancer.
For research use only. We do not sell to patients.
- CAS No.: 1050479-86-1
- Formula: C31H56O4
- Molecular Weight:492.77
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
20(R)-25-Methoxyprotopanaxadiol (20-60 μM; 48 h) potently inhibits human lung cancer A549 cell viability with an IC50 of 8.225 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human lung cancer A549 cells
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Concentration:20 μM, 60 μM
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Incubation Time:48 h
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Result:Showed dose-dependent cytotoxicity against A549 cells, causing nearly maximum mortality at 20 μM and reaching full maximum mortality at 60 μM.
Exhibited an IC50 value of 8.225 μM.
Chemical Information
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CAS No. 1050479-86-1
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Molecular Weight 492.77
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Formula C31H56O4
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SMILES
C[C@]12[C@@](C[C@H]([C@@]3([H])[C@]2(CC[C@]3([H])[C@](C)(O)CCCC(C)(C)OC)C)O)([H])[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC1)C
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Synonyms
20(R)-25-OCH3-PPD
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)