24R-Calcipotriol-d4
24R-Calcipotriol-d4 (PRI 2202-d4; Impurity D of Calcipotriol-d4) is the deuterium labeled 24R-Calcipotriol. 24R-Calcipotriol is an impurity of Calcipotriol. Calcipotriol is a ligand of VDR-like receptors.
For research use only. We do not sell to patients.
- Formula: C27H36D4O3
- Molecular Weight:416.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 112827-99-3
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Molecular Weight 416.63
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Formula C27H36D4O3
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SMILES
C[C@@]12[C@](CC[C@]2([H])[C@H](C)/C=C/[C@@H](C3C([2H])([2H])C3([2H])[2H])O)([H])/C(CCC1)=C/C=C4C([C@H](C[C@@H](C\4)O)O)=C
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Synonyms
PRI 2202-d4; Impurity D of Calcipotriol-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Gocek, Elzbieta; Kielbinski, Marek; Baurska, Hanna et al. Different susceptibilities to 1,25-dihydroxyvitamin D3-induced differentiation of AML cells carrying various mutations. Leukemia Research (2010), 34(5), 649-657. [Content Brief]
[2]. Gocek, Elzbieta; Kielbinski, Marek; Wylob, Paulina et al. Side-chain modified vitamin D analogs induce rapid accumulation of VDR in the cell nuclei proportionately to their differentiation-inducing potential. Steroids (2008), 73(14), 1359-1366. [Content Brief]
[3]. Wietrzyk, Joanna; Nevozhay, Dmitry; Filip, Beata et al. The antitumor effect of lowered doses of cytostatics combined with new analogs of vitamin D in mice. Anticancer Research (2007), 27(5A), 3387-3398. [Content Brief]
[4]. Wietrzyk, Joanna; Chodynski, Michal; Fitak, Hanna et al. Antitumor properties of diastereomeric and geometric analogs of vitamin D3. Anti-Cancer Drugs (2007), 18(4), 447-457. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
24R-Calcipotriol-d4 Related Classifications
HY-166525S Related Classifications
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