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Cat. No.: HY-187138

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3-[(4-Aminobutyl)amino]propanenitrile

3-[(4-Aminobutyl) amino]propanenitrile is a polyamine analog and also a synthetic intermediate. 3-[(4-Aminobutyl) amino]propanenitrile exhibits no growth inhibitory activity against cancer cells in culture medium supplemented with calf serum containing bovine plasma amine oxidase. 3-[(4-Aminobutyl) amino]propanenitrile can be used to prepare N1-substituted spermidine derivatives required for boron neutron capture therapy and positron emission tomography tumor imaging.

For research use only. We do not sell to patients.

CAS No.: 6116-75-2
Formula: C₁₀H₁₃NO
Molecular Weight:163.22

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

3-[(4-Aminobutyl)amino]propanenitrile Chemical Structure

CAS No.: 6116-75-2

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Biological Activity

Description

In Vitro

N-(2-aminoethyl) butane-1,4-diamine (compound 3, x = 4) exhibits weak growth inhibitory activity against KB cells (human epidermoid carcinoma) in medium containing calf serum (with BPAO), with an ID₅₀ > 100 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 6116-75-2
Molecular Weight 163.22
Formula C₁₀H₁₃NO
SMILES

O=C1C2=C(NC(=C2C)C)CCC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Israel M, et al. Synthesis of aminoethyl derivatives of alpha, omega-alkylenediamines and structure-activity relationships for the polyamine-bovine plasma amine oxidase system. J Med Chem. 1971 Nov;14(11):1042-7.

[2]. Martin B, et al. N-Benzylpolyamines as vectors of boron and fluorine for cancer therapy and imaging: synthesis and biological evaluation. Journal of medicinal chemistry. 2001 Oct 25;44(22):3653-64.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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3-[(4-Aminobutyl)amino]propanenitrile

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3-[(4-Aminobutyl)amino]propanenitrile

Biological Activity

Description

In Vitro

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

3-[(4-Aminobutyl)amino]propanenitrile Related Classifications

HY-187138 Related Classifications

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