3-Acetoxytirucalla-7,24-dien-21-oic acid
3-Acetoxytirucalla-7,24-dien-21-oic acid, derived from Boswellia carteri, exhibits anti-inflammatory activity. Its ID50 for Phorbol 12-myristate 13-acetate (HY-18739)-induced ear swelling in mice is 0.06 mg per ear. 3-Acetoxytirucalla-7,24-dien-21-oic acid holds potential for research in the field of inflammation.
For research use only. We do not sell to patients.
- CAS No.: 98166-55-3
- Formula: C32H50O4
- Molecular Weight:498.74
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
0.4 μM
Compound: 10
|
Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured after 1 min by RP-HPLC analysis
Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured after 1 min by RP-HPLC analysis
|
[PMID: 24844534] |
Chemical Information
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CAS No. 98166-55-3
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Molecular Weight 498.74
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Formula C32H50O4
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SMILES
C[C@@]12C3=CC[C@](C(C)([C@@H](CC4)OC(C)=O)C)([H])[C@@]4(C)[C@@]3([H])CC[C@]1([C@](CC2)([H])[C@@H](C(O)=O)CC/C=C(C)\C)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)