3'-beta-Azido-2',3'-dideoxyuridine
3'-beta-Azido-2',3'-dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- CAS No.: 101039-96-7
- Formula: C9H11N5O4
- Molecular Weight:253.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | CC50 |
>250 μM
Compound: 1g; AZU
|
Cytotoxicity in human CEM/0 cells assessed as reduction in cell viability incubated for 4 to 5 days
Cytotoxicity in human CEM/0 cells assessed as reduction in cell viability incubated for 4 to 5 days
|
[PMID: 32515595] |
Chemical Information
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CAS No. 101039-96-7
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Molecular Weight 253.21
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Formula C9H11N5O4
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SMILES
OC[C@@H]1[C@H](N=[N+]=[N-])C[C@H](N2C(NC(C=C2)=O)=O)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)