1. Saccharides and Glycosides
  2. 3'-Methoxypuerarin


Cat. No.: HY-N1978 Purity: 99.75%
Handling Instructions

3'-Methoxypuerarin (3'-MOP) is an isoflavone extracted from radix puerariae that shows neuron protection activity.

For research use only. We do not sell to patients.

3'-Methoxypuerarin Chemical Structure

3'-Methoxypuerarin Chemical Structure

CAS No. : 117047-07-1

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Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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3'-Methoxypuerarin (3'-MOP) is an isoflavone extracted from radix puerariae that shows neuron protection activity.

In Vivo

3'-Methoxypuerarin increases the number of surviving neurons in the hippocampal CA1 region and markedly reduces the number of apoptotic pyramidal neurons after ischemia/reperfusion injury. 3'-Methoxypuerarin can protect hippocampal neurons against I/R injury by inhibiting apoptosis[1].

Molecular Weight







O=C1C(C2=CC=C(O)C(OC)=C2)=COC3=C([[email protected]@H]4O[[email protected]@H]([[email protected]]([[email protected]](O)[[email protected]]4O)O)CO)C(O)=CC=C13


Room temperature in continental US; may vary elsewhere.


4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Animal Administration


Male Wistar rats, weighing 260-320 g are randomly divided into three groups (n = 8 per group). [1] I/R+3'-MOP group: the rats undergo 8 minutes of ischemia and then 3 days of reperfusion. The 3'-Methoxypuerarin (60 mg/kg i.p.) is administrated at the moment of clamping of the carotid arteries. The rats receive daily i.p. injection of 3'-Methoxypuerarin for 3 days. [2] I/R group: the rats undergo 8 minutes of ischemia and 72 h of reperfusion. The same volume of solvent (35% polyethylene glycol solution) is administrated in the same way as 3'-Methoxypuerarin. [3] Control group: the rats undergo a sham operation. Vertebral and carotid arteries are exposed but not occluded. The rats receive a daily i.p. injection of 35% polyethylene glycol solution for 3 days[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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