4-Boc-(trans)-Cyclohexanediamine-2-ethyl acetate
Based on 1 Customer Validation
4-Boc-(trans)-Cyclohexanediamine-2-ethyl acetate is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: ≥95.0%
- CAS No.: 946598-34-1
- Formula: C15H27NO4
- Molecular Weight:285.38
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E370 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 946598-34-1
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Appearance Solid
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Molecular Weight 285.38
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Formula C15H27NO4
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SMILES
N(C(OC(C)(C)C)=O)[C@@H]1CC[C@@H](CC(OCC)=O)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (350.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (240 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5041 mL | 17.5205 mL | 35.0410 mL | 87.6025 mL |
| 5 mM | 0.7008 mL | 3.5041 mL | 7.0082 mL | 17.5205 mL | |
| 10 mM | 0.3504 mL | 1.7520 mL | 3.5041 mL | 8.7602 mL | |
| 15 mM | 0.2336 mL | 1.1680 mL | 2.3361 mL | 5.8402 mL | |
| 20 mM | 0.1752 mL | 0.8760 mL | 1.7520 mL | 4.3801 mL | |
| 25 mM | 0.1402 mL | 0.7008 mL | 1.4016 mL | 3.5041 mL | |
| 30 mM | 0.1168 mL | 0.5840 mL | 1.1680 mL | 2.9201 mL | |
| 40 mM | 0.0876 mL | 0.4380 mL | 0.8760 mL | 2.1901 mL | |
| 50 mM | 0.0701 mL | 0.3504 mL | 0.7008 mL | 1.7520 mL | |
| 60 mM | 0.0584 mL | 0.2920 mL | 0.5840 mL | 1.4600 mL | |
| 80 mM | 0.0438 mL | 0.2190 mL | 0.4380 mL | 1.0950 mL | |
| 100 mM | 0.0350 mL | 0.1752 mL | 0.3504 mL | 0.8760 mL |
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