4-Boc-(trans)-Cyclohexanediamine-2-ethyl acetate

Cat. No.: HY-78608 Purity: ≥95.0%: Data Sheet
COA

SDS
Handling Instructions
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4-Boc-(trans)-Cyclohexanediamine-2-ethyl acetate is a PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

4-Boc-(trans)-Cyclohexanediamine-2-ethyl acetate Chemical Structure

CAS No. : 946598-34-1

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Description

4-Boc-(trans)-Cyclohexanediamine-2-ethyl acetate is a PROTAC linker that can be used in the synthesis of PROTACs.

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E370 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

285.38

Formula

C₁₅H₂₇NO₄

CAS No.

946598-34-1

Appearance

Solid

SMILES

N(C(OC(C)(C)C)=O)[C@@H]1CC[C@@H](CC(OCC)=O)CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (350.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5041 mL	17.5205 mL	35.0410 mL
5 mM	0.7008 mL	3.5041 mL	7.0082 mL
10 mM	0.3504 mL	1.7520 mL	3.5041 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥95.0%

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Data Sheet (240 KB) SDS (392 KB)

COA (244 KB) HNMR (220 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.5041 mL	17.5205 mL	35.0410 mL	87.6025 mL
	5 mM	0.7008 mL	3.5041 mL	7.0082 mL	17.5205 mL
	10 mM	0.3504 mL	1.7520 mL	3.5041 mL	8.7602 mL
	15 mM	0.2336 mL	1.1680 mL	2.3361 mL	5.8402 mL
	20 mM	0.1752 mL	0.8760 mL	1.7520 mL	4.3801 mL
	25 mM	0.1402 mL	0.7008 mL	1.4016 mL	3.5041 mL
	30 mM	0.1168 mL	0.5840 mL	1.1680 mL	2.9201 mL
	40 mM	0.0876 mL	0.4380 mL	0.8760 mL	2.1901 mL
	50 mM	0.0701 mL	0.3504 mL	0.7008 mL	1.7520 mL
	60 mM	0.0584 mL	0.2920 mL	0.5840 mL	1.4600 mL
	80 mM	0.0438 mL	0.2190 mL	0.4380 mL	1.0950 mL
	100 mM	0.0350 mL	0.1752 mL	0.3504 mL	0.8760 mL