4'-Chloro-2,2':6',2''-terpyridine
Based on 1 Customer Validation
4'-Chloro-2,2':6',2''-terpyridine (4'-Chloro-α,α',α''-tripyridyl) is a metal-organic framework (MOF).
For research use only. We do not sell to patients.
- Purity: 99.34%
- CAS No.: 128143-89-5
- Formula: C15H10ClN3
- Molecular Weight:267.72
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Storage:
RT, protect from light, stored under nitrogen.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
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1,4-Di([2,2':6',2''-terpyridin]-4'-yl)benzene
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6,6''-Dibromo-2,2':6',2''-terpyridine
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2-Chloroisonicotinaldehyde
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6,6'-Dimethyl-2,2'-bipyridyl
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| COS-7 | EC50 |
>1 mM
Compound: 20
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Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation counting analysis
Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation counting analysis
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[PMID: 22957890] |
| COS-7 | EC50 |
0.39 μM
Compound: 20
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Allosteric modulation at human CCR8 transfected in COS7 cells assessed as [3H]IP3 turnover by liquid scintillation counting analysis
Allosteric modulation at human CCR8 transfected in COS7 cells assessed as [3H]IP3 turnover by liquid scintillation counting analysis
|
[PMID: 22957890] |
| COS-7 | EC50 |
1.2 μM
Compound: 20
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Allosteric modulation at human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as {3H]IP3 turnover by liquid scintillation counting analysis
Allosteric modulation at human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as {3H]IP3 turnover by liquid scintillation counting analysis
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[PMID: 22957890] |
| COS-7 | IC50 |
8.1 μM
Compound: 20
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Displacement of [125I]-CCL3 from human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrs
Displacement of [125I]-CCL3 from human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrs
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[PMID: 22957890] |
Chemical Information
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CAS No. 128143-89-5
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Appearance Solid
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Molecular Weight 267.72
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Formula C15H10ClN3
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Color Off-white to light yellow
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SMILES
ClC=1C=C(N=C(C1)C=2N=CC=CC2)C3=NC=CC=C3
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Synonyms
4'-Chloro-α,α',α''-tripyridyl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, protect from light, stored under nitrogen
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
DMSO : 16.67 mg/mL (62.27 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (244 KB)
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SDS (642 KB)
- English - EN (642 KB)
- Français - FR (642 KB)
- Deutsch - DE (642 KB)
- Norwegian - NO (642 KB)
- Español - ES (642 KB)
- Swedish - SV (642 KB)
- Italian - IT (642 KB)
- Korean - KR (642 KB)
- Portuguese - PT (642 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7352 mL | 18.6762 mL | 37.3525 mL | 93.3811 mL |
| 5 mM | 0.7470 mL | 3.7352 mL | 7.4705 mL | 18.6762 mL | |
| 10 mM | 0.3735 mL | 1.8676 mL | 3.7352 mL | 9.3381 mL | |
| 15 mM | 0.2490 mL | 1.2451 mL | 2.4902 mL | 6.2254 mL | |
| 20 mM | 0.1868 mL | 0.9338 mL | 1.8676 mL | 4.6691 mL | |
| 25 mM | 0.1494 mL | 0.7470 mL | 1.4941 mL | 3.7352 mL | |
| 30 mM | 0.1245 mL | 0.6225 mL | 1.2451 mL | 3.1127 mL | |
| 40 mM | 0.0934 mL | 0.4669 mL | 0.9338 mL | 2.3345 mL | |
| 50 mM | 0.0747 mL | 0.3735 mL | 0.7470 mL | 1.8676 mL | |
| 60 mM | 0.0623 mL | 0.3113 mL | 0.6225 mL | 1.5564 mL |
4'-Chloro-2,2':6',2''-terpyridine Related Classifications
HY-W004586 Related Classifications
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