5’-Azido-2’,5’-dideoxyuridine

Cat. No.: HY-154374 Purity: 98.22%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

5’-Azido-2’,5’-dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

5’-Azido-2’,5’-dideoxyuridine Chemical Structure

CAS No. : 35959-37-6

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

253.21

Formula

C₉H₁₁N₅O₄

CAS No.

35959-37-6

Appearance

Solid

Color

White to off-white

SMILES

O=C(C=C1)NC(N1[C@@H]2O[C@H](CN=[N+]=[N-])[C@@H](O)C2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (394.93 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.9493 mL	19.7465 mL	39.4929 mL
5 mM	0.7899 mL	3.9493 mL	7.8986 mL
10 mM	0.3949 mL	1.9746 mL	3.9493 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.22%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (250 KB) HNMR (131 KB) LCMS (341 KB)

Handling Instructions (2659 KB)

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.9493 mL	19.7465 mL	39.4929 mL	98.7323 mL
	5 mM	0.7899 mL	3.9493 mL	7.8986 mL	19.7465 mL
	10 mM	0.3949 mL	1.9746 mL	3.9493 mL	9.8732 mL
	15 mM	0.2633 mL	1.3164 mL	2.6329 mL	6.5822 mL
	20 mM	0.1975 mL	0.9873 mL	1.9746 mL	4.9366 mL
	25 mM	0.1580 mL	0.7899 mL	1.5797 mL	3.9493 mL
	30 mM	0.1316 mL	0.6582 mL	1.3164 mL	3.2911 mL
	40 mM	0.0987 mL	0.4937 mL	0.9873 mL	2.4683 mL
	50 mM	0.0790 mL	0.3949 mL	0.7899 mL	1.9746 mL
	60 mM	0.0658 mL	0.3291 mL	0.6582 mL	1.6455 mL
	80 mM	0.0494 mL	0.2468 mL	0.4937 mL	1.2342 mL
	100 mM	0.0395 mL	0.1975 mL	0.3949 mL	0.9873 mL