6A-Azido-6A-deoxy-β-cyclodextrin  (Synonyms: β-CDN3; 6A-deoxy-6A-azido-β-cyclodextrin)

6A-Azido-6A-deoxy-β-cyclodextrin (β-CDN3; 6A-deoxy-6A-azido-β-cyclodextrin) is a new water-soluble Schiff base ligand based on β-cyclodextrin (HY-107201). 6a-Azido-6a-deoxy-β-cyclodextrin can be used for biaqueous hydroformylation. β-cyclodextrin (βCD) has a unique affinity for Dexamethasone (HY-14648), and can be used as a topical osmotic enhancer to introduce it into the agent carrier system^[1][2]. 6A-Azido-6A-deoxy-β-cyclodextrin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

1160.00

C₄₂H₆₉N₃O₃₄

98169-85-8

Solid

White to off-white

[N-]=[N+]=NC[C@@H](O[C@@](O[C@]([C@@H]1O)([H])[C@H](O[C@@](O[C@]([C@@H]2O)([H])[C@H](O[C@@](O[C@]([C@@H]([C@H]3O)O)([H])[C@H]4CO)([H])[C@@H]2O)CO)([H])[C@@H]1O)CO)([H])[C@H](O)[C@H]5O)[C@@]5([H])O[C@@]([C@@H]([C@@H](O)[C@]6([H])O[C@@]([C@@H]([C@@H](O)[C@]7([H])O[C@@]([C@@H]([C@@H](O)[C@]8([H])O[C@@]3([H])O4)O)([H])O[C@@H]8CO)O)([H])O[C@@H]7CO)O)([H])O[C@@H]6CO

Room temperature in continental US; may vary elsewhere.

• [1]. Dauchy M, et al. New water-soluble Schiff base ligands based on β-cyclodextrin for aqueous biphasic hydroformylation reaction[J]. Pure and Applied Chemistry, 2018, 90(5): 845-855.

  [2]. Giulbudagian M, et al. Enhanced topical delivery of dexamethasone by β-cyclodextrin decorated thermoresponsive nanogels. Nanoscale. 2017 Dec 21;10(1):469-479.   [Content Brief]