7-(4-Hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one
Based on 1 Customer Validation
7-(4-Hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one is a inhibitor of prostaglandin biosynthesis.
For research use only. We do not sell to patients.
- Purity : 97%
- CAS No.: 79559-60-7
- Formula: C20H22O3
- Molecular Weight:310.39
-
Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
All Endogenous Metabolite Isoforms
More
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| B16 | IC50 |
10 μM
Compound: 2
|
Inhibition of melanogenesis in theophylline-stimulated mouse B16-4A5 cells after 72 hrs
Inhibition of melanogenesis in theophylline-stimulated mouse B16-4A5 cells after 72 hrs
|
[PMID: 19615910] |
| B16-4A5 | IC50 |
60 μM
Compound: 2
|
Inhibition of theophylline-stimulated mouse B16-4A5 cell proliferation assessed as cell viability after 68 hrs by WST8 assay
Inhibition of theophylline-stimulated mouse B16-4A5 cell proliferation assessed as cell viability after 68 hrs by WST8 assay
|
[PMID: 19615910] |
| IMR-32 | IC50 |
0.1 μM
Compound: 2
|
Antiproliferative activity against human IMR-32 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human IMR-32 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 33587631] |
| MCF7 | IC50 |
20.4 μM
Compound: 2
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 33587631] |
| MCF7 | IC50 |
3.9 μM
Compound: 2
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 33587631] |
| RAW264.7 | IC50 |
0.6 μM
Compound: 37
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production incubated for 20 hrs by Griess reagent based microplate reader analysis
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production incubated for 20 hrs by Griess reagent based microplate reader analysis
|
[PMID: 33422907] |
| U2OS | IC50 |
10.7 μM
Compound: 2
|
Antiproliferative activity against human U2OS cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human U2OS cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 33587631] |
Chemical Information
-
CAS No. 79559-60-7
-
Appearance Oil
-
Molecular Weight 310.39
-
Formula C20H22O3
-
Color Colorless to light yellow
-
SMILES
O=C(/C=C/CCC1=CC=C(O)C(OC)=C1)CCC2=CC=CC=C2
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
-
Data Sheet (263 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)