9,13-Epidioxy-8(14)-abieten-18-oic acid
9,13-Epidioxy-8(14)-abieten-18-oic acid is a Diterpenoids product that can be isolated from the heartwoods of Podocarpus macrophyllus.
For research use only. We do not sell to patients.
- CAS No.: 5309-35-3
- Formula: C20H30O4
- Molecular Weight:334.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>10 μM
Compound: 15
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Cytotoxicity in human A549 cells by SRB assay
Cytotoxicity in human A549 cells by SRB assay
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[PMID: 26812172] |
| BV-2 | IC50 |
34.7 μM
Compound: 4
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Inhibition of LPS-induced NO production in mouse BV2 cells after 20 hrs by Griess assay
Inhibition of LPS-induced NO production in mouse BV2 cells after 20 hrs by Griess assay
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[PMID: 27989668] |
| BV-2 | IC50 |
57.3 μM
Compound: 15
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Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess assay
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess assay
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[PMID: 26812172] |
| HCT-116 | IC50 |
>10 μM
Compound: 15
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Cytotoxicity in human HCT116 cells by SRB assay
Cytotoxicity in human HCT116 cells by SRB assay
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[PMID: 26812172] |
| HEK293 | IC50 |
>100 μg/mL
Compound: 38
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Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells
Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells
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[PMID: 20022253] |
| LoVo | IC50 |
>25 μg/mL
Compound: 38
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Antiproliferative activity against human LoVo cells
Antiproliferative activity against human LoVo cells
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[PMID: 20022253] |
| QGY-7703 | IC50 |
>25 μg/mL
Compound: 38
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Antiproliferative activity against human QGY7703 cells
Antiproliferative activity against human QGY7703 cells
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[PMID: 20022253] |
| RAW264.7 | IC50 |
>100 μg/mL
Compound: 38
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Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release
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[PMID: 20022253] |
| SK-MEL-2 | IC50 |
>10 μM
Compound: 15
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Cytotoxicity in human SK-MEL-2 cells by SRB assay
Cytotoxicity in human SK-MEL-2 cells by SRB assay
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[PMID: 26812172] |
| SK-OV-3 | IC50 |
>10 μM
Compound: 15
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Cytotoxicity in human SKOV3 cells by SRB assay
Cytotoxicity in human SKOV3 cells by SRB assay
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[PMID: 26812172] |
Chemical Information
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CAS No. 5309-35-3
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Molecular Weight 334.45
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Formula C20H30O4
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SMILES
C[C@@]12[C@@]34C(CC[C@@]1([H])[C@@](C)(CCC2)C(O)=O)=C[C@@](CC3)(OO4)C(C)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
9,13-Epidioxy-8(14)-abieten-18-oic acid Related Classifications
HY-N2791 Related Classifications
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