1. Natural Products
  2. Plants
  3. Labiatae
  4. Coleus forskohlii (Willd.) Briq.

Coleus forskohlii (Willd.) Briq.

Coleus forskohlii (Willd.) Briq. (2):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15371
    Forskolin 66575-29-9 99.82%
    Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase. Forskolin is also an inducer of intracellular cAMP formation. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy.
    Forskolin
  • HY-N6927
    Isoforskolin 64657-21-2
    Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis.
    Isoforskolin