- Natural Products
- Plants
- Leguminosae
- Pueraria montana (Lour.) Merr.
Pueraria montana (Lour.) Merr.
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Pueraria montana (Lour.) Merr. (15)
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- Formula: C22H34O7
- Molecular Weight: 410.50
Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase. Forskolin is also an inducer of intracellular cAMP formation. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy.
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- Formula: C22H34O7
- Molecular Weight: 410.50
Forskolin (Standard) is the analytical standard of Forskolin. This product is intended for research and analytical applications. Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase. Forskolin is also an inducer of intracellular cAMP formation. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy.
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- Formula: C22H34O7
- Molecular Weight: 410.50
Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis.
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- Formula: C22H34O6
- Molecular Weight: 394.50
9-Deoxyforskolin (compound 2) is a labdane-type diterpenoid, and also a forskolin derivative identified in hairy root cultures of Coleus forskohlii.
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- Formula: C24H36O7
- Molecular Weight: 436.54
Forskolin G is a Diterpenoids product that can be isolated from the herbs of Coleus forskohlii.
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- Formula: C20H30O3
- Molecular Weight: 318.45
Demethylsalvicanol ((+)-Demethylsalvicanol), a diterpene, is a anticancer agent with an IC50 of 0.71 μg/mL against P388 murine leukemia cells. Demethylsalvicanol induces cytotoxic activity against leukemia cells and insect Sf9 cells. Demethylsalvicanol acts as an antifeedant against Leptinotarsa decemlineata. Demethylsalvicanol can be used for the research of leukemia.
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- Formula: C22H20O12
- Molecular Weight: 476.39
Scutellarein 4'-methyl ether 7-O-glucuronide (Clerodendroside) is a flavonoid inhibitor of acetylcholinesterase (AChE) (IC50=1 mg/mL). Scutellarein 4'-methyl ether 7-O-glucuronide can be isolated from Plectranthus barbatus. It also possesses antioxidant activity and can be used in research on neurological diseases such as Alzheimer's disease.
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- Formula: C22H34O5
- Molecular Weight: 378.50
1,9-Dideoxyforskolin is an inactive analog of forskolin.
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- Formula: C8H14O6
- Molecular Weight: 206.19
Ethyl β-D-ribo-hexopyranosid-3-ulose (Compound 2) is a natural product that can be isolated from Coleus forskohlii.
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- Formula: C30H30O7
- Molecular Weight: 502.56
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- Formula: C22H34O7
- Molecular Weight: 410.50
Isoforskolin (Standard) is the analytical standard of Isoforskolin. This product is intended for research and analytical applications. Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis.
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- Formula: C20H32O6
- Molecular Weight: 368.46
Deacetylforskolin is a deacetylated derivative of forskolin (HY-15371) that can be extracted from C. forskohlii. Deacetylforskolin activates rat adipocyte adenylyl cyclase (IC50 = 20 µM), inhibits glucose transport in rat adipocyte plasma membranes and exhibits antihypertensive activity.
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- Formula: C27H30O16
- Molecular Weight: 610.52
3′-Hydroxytectorigenin-7-O-β-D-xylosyl-(1→6)-β-D-glucopyranoside is an antioxidant that can be found in Pueraria montana var. lobata. It exhibits DPPH radical scavenging activity, with an IC50 value of 42 μg/mL.
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- Formula: C24H36O8
- Molecular Weight: 452.54
Forskolin J (6-Acetylforskolin) is a product that can be isolated from .
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- Formula: C20H28O5
- Molecular Weight: 348.43
6-Epidemethylesquirolin D (6-epi-O-Demethylesquirolin D) is a Diterpenoids product that can be isolated from the herbs of Euphorbia ehracteolata.
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