Deacetylforskolin
Based on 1 Customer Validation
Deacetylforskolin is a deacetylated derivative of forskolin (HY-15371) that can be extracted from C. forskohlii. Deacetylforskolin activates rat adipocyte adenylyl cyclase (IC50 = 20 µM), inhibits glucose transport in rat adipocyte plasma membranes and exhibits antihypertensive activity.
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- Pureté : 99.9%
- CAS No.: 64657-20-1
- Formule: C20H32O6
- Masse moléculaire:368.46
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
Description
Chemical Information
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CAS No. 64657-20-1
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Appearance Solid
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Masse moléculaire 368.46
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Formule C20H32O6
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Color White to off-white
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SMILES
O[C@@]([C@@]([C@H]1O)(O[C@@]2(C)C=C)C)(C(C2)=O)[C@]([C@@](C3(C)C)([H])[C@@H]1O)([C@H](CC3)O)C
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Synonyms
7-Deacetylforskolin
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Structure Classification
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Protocole
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Large-size fat particle sorting
Large-size fat particle sorting is widely used to isolate cells up to 200 μm in diameter. Single-cell flow sorting will allow greater insight into adipocyte heterogeneity by identifying gene expression, protein composition, and metabolic signatures at the single-cell level.
Pureté et documentation
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Fiche technique (278 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Joost HG, et al. Activation of adenylate cyclase and inhibition of glucose transport in rat adipocytes by forskolin analogues: structural determinants for distinct sites of action. Mol Pharmacol. 1988 Apr;33(4):449-53. [Content Brief]
[2]. Bhat SV, et al. The antihypertensive and positive inotropic diterpene forskolin: effects of structural modifications on its activity. J Med Chem. 1983 Apr;26(4):486-92. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)