Deacetylforskolin
Deacetylforskolin is a deacetylated derivative of forskolin (HY-15371) that can be extracted from C. forskohlii. Deacetylforskolin activates rat adipocyte adenylyl cyclase (IC50 = 20 µM), inhibits glucose transport in rat adipocyte plasma membranes and exhibits antihypertensive activity.
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- CAS 番号: 64657-20-1
- 分子式: C20H32O6
- 分子量:368.46
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
化学情報
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CAS 番号 64657-20-1
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分子量 368.46
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分子式 C20H32O6
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SMILES
O[C@@]([C@@]([C@H]1O)(O[C@@]2(C)C=C)C)(C(C2)=O)[C@]([C@@](C3(C)C)([H])[C@@H]1O)([C@H](CC3)O)C
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別名
7-Deacetylforskolin
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Joost HG, et al. Activation of adenylate cyclase and inhibition of glucose transport in rat adipocytes by forskolin analogues: structural determinants for distinct sites of action. Mol Pharmacol. 1988 Apr;33(4):449-53. [Content Brief]
[2]. Bhat SV, et al. The antihypertensive and positive inotropic diterpene forskolin: effects of structural modifications on its activity. J Med Chem. 1983 Apr;26(4):486-92. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)