Hypericum uralum Buch.-Ham. & D. Don
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Hypericum uralum Buch.-Ham. & D. Don (3)
- Formula: C38H50O5
- Molecular Weight: 586.80
Uralione E is a naturally occurring polycyclic polyprenylated acylphloroglucinol (PPAP). Uralione E exhibits a protective effect against corticosterone (HY-B1618)-induced damage in PC12 cells. In a free fatty acid (FFA)-induced L02 cell model, Uralione E dose-dependently reduces intracellular lipid accumulation, downregulates the expression of FASN and CD36, and upregulates the expression of ACOX1 and PPARα. Uralione E can be used in studies related to neuronal cell damage, lipid metabolism, and non-alcoholic steatohepatitis.
- Formula: C38H52O7
- Molecular Weight: 620.82
Uralione D is a neuroprotective agent found in Hypericum uralum and Hypericum kouytchense. Uralione D exhibits cytotoxic activity against gastric cancer cells and protects against Corticosterone (HY-B1618)-induced damage in neuron-like cells. Uralione D is useful for research on depression, multidrug-resistant liver cancer, and gastric cancer.
- Formula: C38H52O7
- Molecular Weight: 620.82
Uralione I is a polycyclic polyprenylated acylphloroglucinol (PPAP) found in the whole plant of Hypericum uralum. Uralione I can be used for research on depression.
