Others

Boc-PIP-Me-CH2-2,7-diazaspiro[3.5]nonane is the linker of PROTAC K-Ras Degrader-3 (HY-168054), which can be used in the synthesis of PROTACs.

ERAP1-IN-2 (compound 3f) is an inhibitor of ERAP1 (endoplasmic reticulum aminopeptidase 1). ERAP1-IN-2 has an IC₅₀ value of 1.72 μM against hERAP1.

6-Hydroxy-2′-methoxyflavone is an active molecule.

Ap4dT is an inhibitor for human adenylate kinase isozyme 1 (hAK1), that inhibits the ATP and ADP synthesis with IC₅₀s of 42 μM and 38 μM.

Desmethylflutiazepam (N-Desmethylfludiazepam) is a metabolite of various benzodiazepine compounds.

4'-Fluoro diazepam is a 1,4-benzodiazepine compound. 4'-Fluoro diazepam is structurally similar to Diazepam, but its has only minimal biological activity.

exo-Tetrahydrocannabivarin (Compound 12) is a Δ^9,11-THC analogue. exo-Tetrahydrocannabivarin weakly binds to cannabinoid receptors (CB) (IC₅₀: 1.4 μM). exo-Tetrahydrocannabivarin is active on both motor and analgesic aspects in mice.

Fluo-4 potassium is a cell-impermeable Ca²⁺ (calcium ion) indicator (λ_ex=494 nm, λ_em=516 nm). Fluo-4 potassium can be introduced into cells using methods such as patch clamping and microinjection.

DLAC is a detergent synthesized from Lactobionic acid (HY-N7059). DLAC can be used to solubilize membrane proteins, with a critical micelle concentration (CMC) of 1.3 mM.

Lipid C3 can be used to synthesize lipid-like nanoparticles (LNPs) for delivery of mRNA.

5R(6S)-EET is the metabolite of Arachidonic acid (HY-109590). 5R(6S)-EET activates the synthesis of endogenous prostaglandin (PGE2), which inhibits the Na⁺ absorption, increases the intracellular Ca²⁺, and promotes the depolarization of transmembrane voltage. 5R(6S)-EET exhibits stereoselectivity with less effectness than 5S(6R)-EET (HY-168382A).

5S(6R)-EET is the metabolite of Arachidonic acid (HY-109590). 5S(6R)-EET activates the synthesis of endogenous prostaglandin (PGE2), which inhibits the Na⁺ absorption, increases the intracellular Ca²⁺, and promotes the depolarization of transmembrane voltage. 5S(6R)-EET is more active than 5R(6S)-EET (HY-168382).

1,3-Dimyristoyl-2-oleoylglycerol is a crystal structure of the beta1 polymorphs of mono-unsaturated triacylglycerols.

1,2-Dipalmitoyl-3-Myristoyl-rac-glycerol is a triacylglycerol in which palmitic acid (HY-N0830) is located at the sn-1 and sn-2 positions, and myristic acid (HY-N2041) is at the sn-3 position. It can be found in bovine milk fat.

1,2-Stearin-3-linolein is a triacylglycerol. 1,2-Stearin-3-linolein has Stearic acid (HY-B2219) at sn-1 and sn-2 positions, and contains Linoleic acid (HY-N0729) at sn-3 position.

1-Lauroyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol with Lauric acid (HY-Y0366), Oleic acid (HY-N1446), and Palmitic acid (HY-N0830) at the sn-1, sn-2 and sn-3 positions, respectively.

Propylene glycol monopalmitate can be used to synthesize solid lipid nanoparticles (SLNs) for the delivery of bioactive compounds.

1,2-Dipalmitoyl-3-stearoyl-rac-glycerol (1,2-Palmitin-3-stearin) is a triacylglycerol found in ostrich and emu oils as well as cow milk fat. The sn-1 and sn-2 positions of 1,2-Dipalmitoyl-3-stearoyl-rac-glycerol contain palmitic acid (HY-N0830), and the sn-3 position contains stearic acid (HY-B2219).

Glioroseinol is a fungal metabolite that can be found in Gliocladium, and is a derivative of Gliorosein (HY-N10228).

Herbicidal agent 8 (Compound 9w) targets the auxin indole-3-acetic acid (IAA, IC₅₀=4.389 μM), disrupting the physiological activities of plant cells and eventually causing plant death. Herbicidal agent 8 exhibits herbicidal activity against broadleaf weeds and grass weeds.