Ap4dT
Ap4dT is an inhibitor for human adenylate kinase isozyme 1 (hAK1), that inhibits the ATP and ADP synthesis with IC50s of 42 μM and 38 μM.
For research use only. We do not sell to patients.
- CAS No.: 13457-68-6
- Formula: C20H29N7O20P4
- Molecular Weight:811.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| L1210 | IC50 |
15 μM
Compound: Ap4T
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Concentration required to reduce thymidine kinase rate by 50% in L1210 cells
Concentration required to reduce thymidine kinase rate by 50% in L1210 cells
|
[PMID: 2838631] |
| L1210 | IC50 |
77 μM
Compound: Ap4T
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Concentration required to reduce Ribonucleotide reductase rate by 50% in L1210 cells
Concentration required to reduce Ribonucleotide reductase rate by 50% in L1210 cells
|
[PMID: 2838631] |
Chemical Information
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CAS No. 13457-68-6
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Molecular Weight 811.37
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Formula C20H29N7O20P4
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SMILES
O[C@@H]1[C@H](O)[C@@H](COP(OP(OP(OP(OC[C@@H](O2)[C@@H](O)C[C@@H]2N3C(NC(C(C)=C3)=O)=O)(O)=O)(O)=O)(O)=O)(O)=O)O[C@H]1N4C5=NC=NC(N)=C5N=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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