2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Acyltransferase
  5. DGAT1 Isoform
  6. DGAT1 Inhibitor

DGAT1 Inhibitor

DGAT1 Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-153507
    DGAT1-IN-4
    		Inhibitor
    DGAT1-IN-4 is a potent, orally active, and selective DGAT1 inhibitor with an IC50 of 17 nM. DGAT1-IN-4 exhibits >588-fold selectivity over DGAT2. DGAT1-IN-4 suppresses intracellular triglyceride synthesis in mouse myoblast cells. DGAT1-IN-4 suppresses body weight gain in diet-induced obese dogs. DGAT1-IN-4 can be used for the research of obesity.
  • HY-N16614
    Ent-Calquiquelignan E
    		Inhibitor
    Ent-Calquiquelignan E (Compound 8) is a flavonoid lignan compound. Ent-Calquiquelignan E can selectively inhibit diacylglycerol acyltransferase 1 (DGAT1) with an IC50 of 71.5 μM. Ent-Calquiquelignan E can be used for the research of metabolic diseas.