NOD1 Antagonist
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NOD2 antagonist 1
0 ImagesNOD2 antagonist 1 is a selective NOD2 antagonist with an IC50 of 5.23 μM. NOD2 antagonist 1 acts directly on the NOD2 protein, downregulates the secretion of pro-inflammatory cytokines such as IL-8 and TNF-α, and inhibits the synergistic cross-response of inflammation mediated by NOD2 and TLR4. NOD2 antagonist 1 can be used in studies related to immunity and inflammation.
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NOD1 antagonist-1
0 ImagesCat. No.: HY-163274CAS No.: 3030588-37-2
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NOD1/2 antagonist-1
0 ImagesCat. No.: HY-146034CAS No.: 2704623-69-6NOD1/2 antagonist-1 (compound 36b) is a potent NOD1/2 (nucleotide-binding oligomerization domain-like receptor 1/2) dual antagonist, with IC50 values of 1.13 (NOD1) and 0.77 μM (NOD2), respectively. NOD1/2 antagonist-1 has a acceptable T1/2 (67.6 min). NOD1/2 antagonist-1 (compound 36b) can improve the antitumor efficacy of Paclitaxel (PTX).
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NOD1/2 antagonist-2
0 ImagesCat. No.: HY-101927CAS No.: 2101736-25-6
