NOD1 antagonist-1
NOD1 antagonist-1 (compound 37) exhibits an antagonistic activity towards NOD1 and a weak NOD1/NOD2 selectivity, with IC50s of 9.18 μM and 20.8 μM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 3030588-37-2
- Formula: C24H32N4O2S
- Molecular Weight:440.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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NOD1 9.18 μM (IC50) |
NOD2 20.8 μM (IC50) |
NOD1 antagonist-1 (25 μM, 1 h) inhibits the NF-kB transcriptional activation in HEK-Blue cells with low cytotoxicity (25 μM, 18 h)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HEK-Blue
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Concentration:25 μM
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Incubation Time:18 h
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Result:Maintained a residual metabolic activity of over 80%.
Chemical Information
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CAS No. 3030588-37-2
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Molecular Weight 440.60
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Formula C24H32N4O2S
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SMILES
CC1=CC=C(S(N2C3=CC=CC=C3C(N4CCN(CC4)C)=C2NC(C)(C)C)(=O)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NOD1 antagonist-1 Related Classifications
HY-163274 Related Classifications
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