Neuropeptide Y Receptor Inhibitor

Mibavademab is a CHO-expressed humanized antibody that targets LEPR/CD295. Mibavademab is equipped with a huIgG4SP heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145.58 kDa. The isotype control for Mibavademab can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).

RTI-118 is a novel small-molecule neuropeptide S receptor (NPSR) antagonist. RTI-118 can relieve agent addiction including selectively decrease self-administration.

Npy1r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Npy1r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

NPY1R Human Pre-designed siRNA Set A contains three designed siRNAs for NPY1R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Npy5r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Npy5r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

NPY2R Human Pre-designed siRNA Set A contains three designed siRNAs for NPY2R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

BIBO3304 (diTFA) is an orally effective and selective neuropeptide Y (NPY) Y1 receptor antagonist. BIBO3304 (diTFA) has a high affinity for both human and rat Y1 receptors, with IC₅₀ values of 0.38 and 0.72 nM, respectively. BIBO3304 (diTFA) promotes bone-tendon healing through the Wnt/β-catenin signaling pathway.

GEP44 is a peptide biased triple agonist targeting Glucagon-like peptide 1 receptor (GLP-1R), neuropeptide Y1 Receptor (Y1-R), and neuropeptide Y2 Receptor (Y2-R). GEP44 induces Y1-R antagonist-controlled, GLP-1R-dependent stimulation of insulin secretion in both rat and human pancreatic islets by counteracting effects of Y1-R and GLP-1R agonism. GEP44 promotes insulin-independent Y1-R-mediated glucose uptake in muscle tissue and significantly reduces food intake and body weight in diet-induced obese rat models. GEP44 can be used for obesity and type 2 diabetes mellitus research.

NPY2R Rat Pre-designed siRNA Set A contains three designed siRNAs for NPY2R gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Npy4r Rat Pre-designed siRNA Set A contains three designed siRNAs for Npy4r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

NPY4R Human Pre-designed siRNA Set A contains three designed siRNAs for NPY4R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Npy4r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Npy4r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Npy5r Rat Pre-designed siRNA Set A contains three designed siRNAs for Npy5r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Npy1r Rat Pre-designed siRNA Set A contains three designed siRNAs for Npy1r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Npy2r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Npy2r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.