Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
All Product Categories
-
Parasite Related Products (2499)
Related Products (2499)
-
Related Compound Screening Libraries (1)
-
Parasite Isoform Comparison
-
Thalidasine
0 ImagesCat. No.: HY-N15413CAS No.: 16623-56-6Thalidasine (compound 3) is a bisbenzyltetrahydroisoquinoline alkaloid. Thalidasine is a anticancer agent against human colon adenocarcinoma cells. Thalidasine exhibits antileishmanial activity and can be used for Leishmania infection research research.
-
Clofentezine (Standard)
0 ImagesClofentezine (Standard) is the analytical standard of Clofentezine. This product is intended for research and analytical applications. Clofentezine is a growth inhibitor that is highly lethal to mites.
-
Acridine Orange hydrochloride (Standard)
0 ImagesAcridine Orange hydrochloride (Standard) is the analytical standard of Acridine Orange hydrochloride (HY-101879). This product is intended for research and analytical applications. Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm).
-
Antiparasitic agent-27
0 ImagesCat. No.: HY-175364CAS No.: 3048504-54-4Antiparasitic agent-27 (Compound 2) is a potent antiparasitic agent targeting Leishmania infantum (IC50=3.1 μM). Antiparasitic agent-27 induces G0/G1 cell cycle arrest and reactive oxygen species (ROS) generation to trigger programmed cell death. Antiparasitic agent-27 is promising for research of visceral leishmaniasis (VL).
-
Diclazuril potassium
0 ImagesCat. No.: HY-B0357ACAS No.: 112209-98-0Synonyms: R-64433 potassiumDiclazuril (R-64433) potassium, a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril potassium can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al.
-
2',6'-Dihydroxy-4'-methoxydihydrochalcone
0 ImagesCat. No.: HY-N8691CAS No.: 35241-55-52',6'-Dihydroxy-4'-methoxydihydrochalcone is an orally active dihydrochalcone compound with antiplasmodial and anti-inflammatory activities. 2',6'-Dihydroxy-4'-methoxydihydrochalcone reduces the IL-1β, TNF, and nitrite levels in vitro.
-
Anticoccidial agent-1
0 ImagesCat. No.: HY-183528CAS No.: 762172-81-6Anticoccidial agent-1 is an imidazopyridine anticoccidial agent with an IC50 of 0.044. Anticoccidial agent-1 can be used for the research of coccidiosis.
-
GPCR antagonist-2
0 ImagesCat. No.: HY-187528GPCR antagonist-2 is a GPCR antagonist with macrofilaricidal activity. GPCR antagonist-2 shows inhibitory effects on Brugia pahangi adult females and males (IC50 = 3.9 μM and 2.8 μM, respectively) and Onchocerca ochengi adult females and males (IC50 = 0.35 μM and 1.7 μM, respectively). GPCR antagonist-2 reduces B. pahangi worm burden and affects female fecundity and embryogenesis, downregulates GPCR expression in surviving adult female worms and can be used for the study of filarial infections, including onchocerciasis (river blindness).
-
Ro 19-9638
0 ImagesCat. No.: HY-125632CAS No.: 116370-29-7Ro 19-9638 is the major metabolite of Ro 15-0216. Ro 19-9638 exhibits antiparasitic efficacy against Trypanosoma brucei rhodesiense with an IC50 of 0.0341 µg/mL.
-
Cruzain-IN-1 (Standard)
0 ImagesCat. No.: HY-10836RCAS No.: 1199523-24-4Cruzain-IN-1 (Standard) is the analytical standard of Cruzain-IN-1 (HY-10836). This product is intended for research and analytical applications. Cruzain-IN-1 is a covalent and reversible Cruzain inhibitor, with an IC50 of 10 nM.
-
Sanguinarine chloride (Standard)
0 ImagesSynonyms: Sanguinarin chloride (Standard); Sanguinarium chloride (Standard); Pseudochelerythrine chloride (Standard)Sanguinarine (chloride) (Standard) is the analytical standard of Sanguinarine (chloride). This product is intended for research and analytical applications. Sanguinarine (Sanguinarin) chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.
-
Milbemycin α12
0 ImagesCat. No.: HY-N15093CAS No.: 123071-17-0Milbemycin α12 is an antibiotic and has the effect of killing nematodes and mites.
-
PI4K-IN-3
0 ImagesCat. No.: HY-178775PI4K-IN-3 (Compound 27) is an orally active PI4K inhibitor with an IC50 of 1.9 nM for Plasmodium vivax PI4K. PI4K-IN-3 has no hERG channel inhibition and mammalian cytotoxicity. PI4K-IN-3 has significant selectivity against the human MINK1 and MAP4K4 kinases but with low selectivity against human PI3Kα and PI4Kβ. PI4K-IN-3 has potent antimalarial activity and significantly reduces parasitaemia in NSG mice mouse models of Plasmodium falciparum malaria.
-
Pentamidine (Standard)
0 ImagesPentamidine (Standard) is the analytical standard of Pentamidine. This product is intended for research and analytical applications. Pentamidine (MP-601205) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities.
-
Niclosamide olamine (Standard)
0 ImagesSynonyms: BAY2353 olamine (Standard)Crocin (Standard) is the analytical standard of Crocin. This product is intended for research and analytical applications. Crocin (Crocin I) is an orally active natural product that can be isolated from the stigma of Crocus sativus. Crocin inhibits tumor cell proliferation and promotes apoptosis through JAK pathway. Crocin has anti-inflammatory, antioxidant and antitumor activities .
-
Ornidazole (Standard)
0 ImagesSynonyms: Ro 7-0207 (Standard)Ornidazole (Standard) is the analytical standard of Ornidazole. This product is intended for research and analytical applications. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease.
-
Carmaphycin-17
0 ImagesCat. No.: HY-171956CAS No.: 2143080-91-3Carmaphycin-17 (CP-17) is a selective 20S proteasome inhibitor with an EC50 of 217 ?nM. Carmaphycin-17 has potent antimicrobial activity against Trichomonas vaginalis. Carmaphycin-17 overcomes Metronidazole (HY-B0318) resistance and significantly reduces parasite burden upon topical treatment without any apparent adverse effects in vaginal trichomonad infection mice model. Carmaphycin-17 can be used for sexually transmitted disease like trichomoniasis research.
-
Stilbazium iodide
0 ImagesStilbazium iodide is an orally effective pyridinium quaternary ammonium repellent. Stilbazium (iodide) exhibits broad-spectrum activity against a variety of human and animal intestinal parasites. Stilbazium iodide eliminates both mature and immature worms, reduces egg counts, reddens feces, and causes mild gastrointestinal irritation. Stilbazium iodide can be used in research related to intestinal parasitic infections including pinworm, whipworm, and strongyloidiasis.
-
Cycotiamine
0 ImagesCat. No.: HY-W742094CAS No.: 6092-18-8Cycotiamine is an S-acylated thiamine derivative with antiplasmodial activity. Cycotiamine inhibits the proliferation of Plasmodium falciparum and Plasmodium knowlesi. Cycotiamine can be used in malaria-related research.
-
Nitazoxanide (Standard)
0 ImagesSynonyms: NTZ (Standard); NSC 697855 (Standard)Nitazoxanide (Standard) is the analytical standard of Nitazoxanide. This product is intended for research and analytical applications. Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC50 of 2.4 μM. Nitazoxanide can be used for the research of parasitic gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model.
