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Cruzain-IN-1 

Cat. No.: HY-10836 Purity: 99.94%
Handling Instructions

Cruzain-IN-1 is a covalent and reversible Cruzain inhibitor, with an IC50 of 10 nM.

For research use only. We do not sell to patients.

Cruzain-IN-1 Chemical Structure

Cruzain-IN-1 Chemical Structure

CAS No. : 1199523-24-4

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 165 In-stock
Estimated Time of Arrival: December 31
5 mg USD 150 In-stock
Estimated Time of Arrival: December 31
10 mg USD 240 In-stock
Estimated Time of Arrival: December 31
50 mg USD 750 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1200 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Cruzain-IN-1 is a covalent and reversible Cruzain inhibitor, with an IC50 of 10 nM.

IC50 & Target

IC50:10 nM (Cruzain)[1].

Solvent & Solubility
In Vitro: 

DMSO : 80 mg/mL (266.43 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3303 mL 16.6517 mL 33.3034 mL
5 mM 0.6661 mL 3.3303 mL 6.6607 mL
10 mM 0.3330 mL 1.6652 mL 3.3303 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 2.67 mg/mL (8.89 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.67 mg/mL (8.89 mM); Clear solution

References
Molecular Weight

300.27

Formula

C₁₄H₁₀F₂N₆

CAS No.

1199523-24-4

SMILES

CCN1C2=NC(C#N)=NC(NC3=CC(F)=CC(F)=C3)=C2N=C1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

Product Name:
Cruzain-IN-1
Cat. No.:
HY-10836
Quantity:

Cruzain-IN-1

Cat. No.: HY-10836