Antiparasitic agent-27
Antiparasitic agent-27 (Compound 2) is a potent antiparasitic agent targeting Leishmania infantum (IC50=3.1 μM). Antiparasitic agent-27 induces G0/G1 cell cycle arrest and reactive oxygen species (ROS) generation to trigger programmed cell death. Antiparasitic agent-27 is promising for research of visceral leishmaniasis (VL).
For research use only. We do not sell to patients.
- CAS No.: 3048504-54-4
- Formula: C15H16N4O2
- Molecular Weight:284.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| THP-1 | CC50 |
1074 μM
Compound: 12
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Cytotoxicity against human THP-1 cells assessed as reduction in cell viability incubated for 72 hrs by alamarblue staining based analysis
Cytotoxicity against human THP-1 cells assessed as reduction in cell viability incubated for 72 hrs by alamarblue staining based analysis
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[PMID: 37156183] |
Chemical Information
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CAS No. 3048504-54-4
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Molecular Weight 284.31
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Formula C15H16N4O2
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SMILES
O=C(C1=CC=C(O)C=C1)N2CCN(C3=NC=CN=C3)CC2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antiparasitic agent-27 Related Classifications
HY-175364 Related Classifications
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