35241-55-5
35241-55-5
Chemical Structure
2',6'-Dihydroxy-4'-methoxydihydrochalcone
- CAS No.: 35241-55-5
- Formula:C16H16O4
- Molecular Weight:272.30
IUPAC Name: 1-(2,6-dihydroxy-4-methoxyphenyl)-3-phenylpropan-1-one
InChIKey: MDMCODCJMHTFIZ-UHFFFAOYSA-N
SMILES: O=C(C1=C(O)C=C(OC)C=C1O)CCC2=CC=CC=C2
Biological Activity: 2',6'-Dihydroxy-4'-methoxydihydrochalcone is an orally active dihydrochalcone compound with antiplasmodial and anti-inflammatory activities. 2',6'-Dihydroxy-4'-methoxydihydrochalcone reduces the IL-1β, TNF, and nitrite levels in vitro[1][2].
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2',6'-Dihydroxy-4'-methoxydihydrochalcone | 2',6'-Dihydroxy-4'-methoxydihydrochalcone is an orally active dihydrochalcone compound with antiplasmodial and anti-inflammatory activities. 2',6'-Dihydroxy-4'-methoxydihydrochalcone reduces the IL-1β, TNF, and nitrite levels in vitro. | |||||||||||||||||||||
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References
- [1]. Cerutti ML,et al. Effects of 2',6'-dihydroxy-4'-methoxydihidrochalcone on innate inflammatory response. Naunyn Schmiedebergs Arch Pharmacol. 2020 Nov;393(11):2061-2072. [Content Brief]
- [2]. Bénédicte Portet, et al. Activity-guided isolation of antiplasmodial dihydrochalcones and flavanones from Piper hostmannianum var. berbicense. Phytochemistry. 2007 May;68(9):1312-20. [Content Brief]
