Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2481)
Related Products (2481)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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N-Methyl-4-(8-phenoxyoctoxy)aniline
0 ImagesCat. No.: HY-23317CAS No.: 102759-19-3N-Methyl-4-(8-phenoxyoctoxy) aniline (Compound 3568) is an anti-schistosomal agent. N-Methyl-4-(8-phenoxyoctoxy) aniline exhibits definite anti-Schistosoma mansoni activity in mouse models, but has high acute toxicity. N-Methyl-4-(8-phenoxyoctoxy) aniline can be used in studies related to schistosomiasis.
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Diclazuril-13C3,15N2
0 ImagesCat. No.: HY-W654156Diclazuril-13C3,15N2 is 13C and 15N labeled Diclazuril. Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al.
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Praziquantel (Standard)
0 ImagesPraziquantel (Standard) is the analytical standard of Praziquantel. This product is intended for research and analytical applications. Praziquantel is a broadly effective trematocide and cestocide, the initial effect of praziquantel on the schistosome may be an interaction of the drug with lipid constituents of the tegumental membrane. Praziquantel is used for the research of schistosomiasis.
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GLK7-001
0 ImagesCat. No.: HY-128663CAS No.: 353484-37-4GLK7-001 is a Trypanosoma cruzi glucokinase (TcGlcK) inhibitor. GLK7-001 has in vitro trypanocidal activity.
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WR 30090
0 ImagesCat. No.: HY-180373CAS No.: 19160-62-4WR 30090 (Compound 37) is a broad-spectrum antimalarial agent that does not rely on the classical antifolate pathway. WR 30090 exhibits strong activity against a variety of chloroquine-sensitive and resistant Plasmodium falciparum strains, especially the highly resistant Vietnamese strain. WR 30090 shows high activity in mouse malaria tests, with a minimum effective dose of 5 mg/kg and a minimum cure dose of 20 mg/kg. WR 30090 can be used for research on acute malaria.
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Quinacrine (Standard)
0 ImagesQuinacrine (Standard) is the analytical standard of Quinacrine. This product is intended for research and analytical applications. Quinacrine (Acriquine) is an antimalarial and anti-cancer agent. Quinacrine also inhibits human aldehyde oxidase (IC50: 3.3 μM). Quinacrine has affinity for nucleic acids, and stains DNA and RNA in fixed cells (Ex/Em: 436/525 nm).
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Pefloxacin mesylate (Standard)
0 ImagesSynonyms: Pefloxacinium mesylate (Standard)Pefloxacin mesylate (Standard) (Pefloxacinium mesylate (Standard)) is the analytical standard of Pefloxacin mesylate (HY-B0147A). This product is intended for research and analytical applications. Pefloxacin (Pefloxacinium) mesylate is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin mesylate inhibits DNA relaxation catalyzed by topoisomerase I with an IC50 of 45 μg/mL. Pefloxacin mesylate exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC90s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin mesylate has anti-Plasmodium yoelii infection activity. Pefloxacin mesylate increase UVA-induced edema and immunesuppression. Pefloxacin mesylate can be used for infection studies.
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Antimalarial agent 47
0 ImagesCat. No.: HY-170840Antimalarial agent 47 (compound F14) is an antimalarial compound, with an IC50 of 235 nM for the Plasmodium falciparum W2 strain.
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(±)-Stylopine (Standard)
0 Images(±)-Stylopine (Tetrahydrocoptisine) is an alkaloid compound originally isolated from Corydalis tubers that exhibits anti-inflammatory and anti-parasitic activities.
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Chlorproguanil
0 ImagesChlorproguanil is an antifolate with an IC50 of 4.68 μM against Plasmodium falciparum female gamete formation. Chlorproguanil can be used for the research of malaria.
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Parvaquone
0 ImagesCat. No.: HY-W856920CAS No.: 4042-30-2Parvaquone is an antiparasite agent with an in vitro ED50 of 0.006 mg/L. Parvaquone reduces the proportion of Theileria parva schizont-infected cells. Parvaquone can be used for the research of east coast fever (Theileria parva infection).
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Tetromycin B
0 ImagesCat. No.: HY-126489CAS No.: 180027-84-3Tetromycin B is a cysteine protease inhibitor with Ki values of 0.62, 1.42, 32.5, and 1.59 μM for rhodesain, falcipain-2, cathepsin L, and cathepsin B, respectively. It inhibits the growth of T. brucei in vitro (IC50=30.87 μM). Tetromycin B is also cytotoxic to HEK293T kidney cells and J774.1 macrophages (IC50s=71.77 and 20.2 μM, respectively).
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Lachnumon
0 ImagesCat. No.: HY-125596CAS No.: 150671-02-6Lachnumon is a fungal metabolite with nematicidal and antimicrobial activities.
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(S)-Hydroxychloroquine sulfate
0 ImagesCat. No.: HY-145530CAS No.: 155204-09-4Synonyms: (S)-HCQ sulfate(S)-Hydroxychloroquine ((S)-HCQ) sulfate is an isomer of Hydroxychloroquine (HY-W031727). (S)-Hydroxychloroquine sulfate (2.5-20 mg/mL) reduces the rate of insulin degradation in liver homogenates isolated from non-diabetic and diabetic rats. Formulations containing Hydroxychloroquine have been used in the study of malaria, rheumatoid arthritis, and systemic lupus erythematosus.
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Antileishmanial agent-36
0 ImagesCat. No.: HY-178456CAS No.: 3086122-36-0Antileishmanial agent-36 (compound 4f) is an indole-dihydropyrimidinone derivative with anti-leishmanial activity. Antileishmanial agent-36 induces reactive oxygen species (ROS)-mediated mitochondrial dysfunction and apoptosis. Antileishmanial agent-36 exhibits potent activity against L. donovani (IC50 =4.54 μM) with low cytotoxicity against J774.1 macrophage. Antileishmanial agent-36 clears the parasite burden in a visceral leishmaniasis (VL) model. Antileishmanial agent-36 can be used for VL research.
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Insecticidal agent 6
0 ImagesCat. No.: HY-149697CAS No.: 1699760-76-3Insecticidal agent 6 (Compound Im) is an insect ryanodine receptors (RyRs) inhibitor, with an EC50 value of 0.6308 µM against S. frugiperda RyRs. Insecticidal agent 6 has excellent insecticidal activity against lepidopteran pests and can be used for research on pests and diseases.
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Amodiaquine dihydrochloride (Standard)
0 ImagesSynonyms: Amodiaquin dihydrochloride (Standard)Amodiaquine (dihydrochloride) (Standard) is the analytical standard of Amodiaquine (dihydrochloride). This product is intended for research and analytical applications. Amodiaquine dihydrochloride (Amodiaquin dihydrochloride), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor with a Ki of 18.6 nM. Amodiaquine dihydrochloride is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect.
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RMM23
0 ImagesCat. No.: HY-170219CAS No.: 3113265-82-7RMM23 is an inhibitor targeting PfBDP1 with a Kd value of 1.24 μM. RMM23 against the wild-type strains 3D7 and NF54, and the multidrug-resistant K1 strain in vitro blood stage, with EC50 values of 18 μM, 14 μM, 20 μM, respectively .
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Antileishmanial agent-39
0 ImagesCat. No.: HY-180833Antileishmanial agent-39 (Compound 4h) is an antileishmanial agent. Antileishmanial agent-39 shows antileishmanial activity against the axenic amastigote form of Leishmania infantum with an IC50 of 0.42 μM.
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Antiparasitic agent-39
0 ImagesCat. No.: HY-180943CAS No.: 2568585-37-3Antiparasitic agent-39 (Compound 14) is a selective antiparasitic agent and Deferasirox (HY-17359) derivative. Antiparasitic agent-39 reduces the mitochondrial membrane potential. Antiparasitic agent-39 shows antiparasitic activity against T. brucei, T. gambiense, L. Mexicana, T. gondii, B. divergens, P. falciparum with EC50s of 4.2 nM, 10.4 nM, 52.0 nM, 17.0 nM, 41.2 nM, 54.8 nM, respectively.
