Diclazuril-13C3,15N2
Diclazuril-13C3,15N2 is 13C and 15N labeled Diclazuril. Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al.
For research use only. We do not sell to patients.
- Formula: C1413C3H9Cl3N215N2O2
- Molecular Weight:412.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 101831-37-2
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Molecular Weight 412.60
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Formula C1413C3H9Cl3N215N2O2
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SMILES
ClC1=CC=C(C(C(C(Cl)=CC(N2[15N]=[13CH][13C]([15NH][13C]2=O)=O)=C3)=C3Cl)C#N)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
DMSO : 25 mg/mL (60.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Diaferia, M., et al., Efficacy of toltrazuril 5 % suspension (Baycox(R), Bayer) and diclazuril (Vecoxan(R), Janssen-Cilag) in the control of Eimeria spp. in lambs. Parasitol Res, 2013. 112 Suppl 1: p. 163-8. [Content Brief]
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4237 mL | 12.1183 mL | 24.2365 mL | 60.5914 mL |
| 5 mM | 0.4847 mL | 2.4237 mL | 4.8473 mL | 12.1183 mL | |
| 10 mM | 0.2424 mL | 1.2118 mL | 2.4237 mL | 6.0591 mL | |
| 15 mM | 0.1616 mL | 0.8079 mL | 1.6158 mL | 4.0394 mL | |
| 20 mM | 0.1212 mL | 0.6059 mL | 1.2118 mL | 3.0296 mL | |
| 25 mM | 0.0969 mL | 0.4847 mL | 0.9695 mL | 2.4237 mL | |
| 30 mM | 0.0808 mL | 0.4039 mL | 0.8079 mL | 2.0197 mL | |
| 40 mM | 0.0606 mL | 0.3030 mL | 0.6059 mL | 1.5148 mL | |
| 50 mM | 0.0485 mL | 0.2424 mL | 0.4847 mL | 1.2118 mL | |
| 60 mM | 0.0404 mL | 0.2020 mL | 0.4039 mL | 1.0099 mL |