RSV Inhibitor

Enzaplatovir (Standard) is the analytical standard of Enzaplatovir (HY-109004). This product is intended for research and analytical applications. Enzaplatovir (BTA-C585) is an orally bioavailable Inhibitor for respiratory syncytial virus (RSV) infection.

RSV-IN-13 (compound 24) is a selective RSV fusion protein inhibitor with antiviral activity. RSV-IN-13 has an EC₅₀ of 444.2 nM against RSV A2 strain and a CC₉₀ of 23.7 μM in HepG2 cells. RSV-IN-13 can block the virus from entering host cells. RSV-IN-13 can be used to study RSV infection.

Alizarin complexone (Standard) is the analytical standard of Alizarin complexone (HY-121075). This product is intended for research and analytical applications. Alizarin complexone is a calcium-binding fluorescent dye. Alizarin complexone stains mineralized areas of bone by binding to calcium crystals. Alizarin complexone inhibits the reverse transcriptase activity of RAV-2, HIV-1, and RSV with IC₅₀ values of 3.8 μg/mL, 45 μg/mL, and 100 μg/mL, respectively. Alizarin complexone exhibits antiviral activity against HIV-1 and RSV. Alizarin complexone delays RSV-induced tumor induction in chickens.

Rostafuroxin (Standard) is the analytical standard of Rostafuroxin. This product is intended for research and analytical applications. Rostafuroxin (PST 2238), a digitoxigenin derivative, is an orally active and potent Na+,K+-ATPase (ATP1A1) antognist. Rostafuroxin binds specifically to the ATP1A1 extracellular domain and blocks respiratory syncytial virus (RSV)-triggered EGFR Tyr845 phosphorylation. Rostafuroxin has antihypertensive and anti-RSV activity.

A 33903 is a respiratory syncytial virus (RSV) replication inhibitor. A 33903 can be used for the research of RSV-infection.

HRSV/hCoV-229E-IN-1 (compound 8X) is a potent HRSV and hCoV-229E inhibitor with an IC₅₀ value of 2.1 µM for hCoV-229E. HRSV/hCoV-229E-IN-1 inhibits cell viability.

PC786 (Standard) is the analytical standard of PC786 (HY-102038). This product is intended for research and analytical applications. PC786 is an inhaled respiratory syncytial virus (RSV) L protein polymerase inhibitor. PC786 demonstrates potent antiviral activity against RSV-A (IC₅₀ <0.09 to 0.71 nM) and RSV-B (IC₅₀, 1.3 to 50.6 nM).

Perflubron (Standard) is the analytical standard of Perflubron. This product is intended for research and analytical applications. Perflubron (Perfluorooctyl bromide) is a contrast medium for magnetic resonance imaging and sonography. Perflubron can be emulsified with egg phospholipids (EYP) and shows exceptionally fast excretion characteristics.

ASN-500 is a human monoclonal antibody (mAb) targeting F/Fusion glycoprotein F0. ASN-500 can be used in respiratory syncytial virus infection research.

4,5-O-Dicaffeoyl quinic acid methyl ester (compound 4), a dicaffeoylquinic acid, has potent antiviral activity against respiratory syncytial virus (RSV) with an IC₅₀ of 0.63 μg/mL and a CC₅₀ of 118.68 μg/mL.

JNJ-6231 is a long-acting RSV inhibitor.

(S)-Enzaplatovir (Standard) is the analytical standard of (S)-Enzaplatovir (HY-109004A). This product is intended for research and analytical applications. (S)-Enzaplatovir ((S)-BTA-C585) is the S-enantiomer of Enzaplatovir. (S)-Enzaplatovir shows antiviral activities with an EC₅₀ of 56 nM for respiratory syncytial viral (RSV) (patent WO2011094823A1 compound 77).

CL-A3-7 is a virus-cell fusion inhibitor targeting the RSV F protein. It exerts its effect by blocking the interaction between the virus and the host IGF1R, effectively inhibiting infections of both wild-type RSV and the K394R variant. It is applicable to anti-RSV drug development and resistance-related research.

EVO-46135 is a human monoclonal antibody (mAb) targeting F/Fusion glycoprotein F0. EVO-46135 can be used in Respiratory syncytial virus infections and Metapneumovirus infections research.

RSV/IAV-IN-2 (compound 14c) is a potent and dual inhibitor of RSV/IAV. RSV/IAV-IN-2 has lesser cytotoxicity than the clinical agent, Ribavirin. RSV/IAV-IN-2 has the potential for the research of RSV and/or IAV infections.

RSV/IAV-IN-1 (compound 14e) is a potent and dual inhibitor of RSV/IAV. RSV/IAV-IN-1 has lesser cytotoxicity than the clinical agent, Ribavirin. RSV/IAV-IN-1 has the potential for the research of RSV and/or IAV infections.