2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-119034
    AD-20
    AD-20 is an o-methoxyphenylacetyl dehydroalanine derivative. AD-20 can not only reduce the acute and subchronic toxicity of Doxorubicin (HY-15142A), but also enhance its anti-tumor effect.
    AD-20
  • HY-N17298
    Schisanwilsonin G
    Schisanwilsonin G is a natural product that can be found in dendrobium.
    Schisanwilsonin G
  • HY-114561
    LY 97119
    LY 97119 is an active compound.
    LY 97119
  • HY-119844
    Anidoxime
    Anidoxime is an Amidoxime derivative, and an orally active analgesic agent. Anidoxime can be used for the research of post-surgical pain.
    Anidoxime
  • HY-123157
    Methoserpidine
    Methoserpidine is an active compound.
    Methoserpidine
  • HY-N1856
    3-O-Coumaroylarjunolic acid
    3-O-Coumaroylarjunolic acid is a natural triterpene.
    3-O-Coumaroylarjunolic acid
  • HY-119899
    BO-0742
    BO-0742, a derivative of AHMA and N-mustard, is a potent anti-cancer agent. BO-0742 significantly suppresses the growth of xenografts of human breast and ovarian cancers in mice.
    BO-0742
  • HY-N17382
    Crithmumdiol
    Crithmumdiol is a 17C-acetylene derivative that can be found in Crithmum maritimum L.
    Crithmumdiol
  • HY-N16914
    Isodonhenrin D
    Isodonhenrin D is a natural diterpene.
    Isodonhenrin D
  • HY-N18296
    Karelinine
    Karelinine is a steroidal alkaloid found in the bulbs of Fritillaria ussuriensis Maxim and Fritillaria karelinii. Karelinine shows accelerated absorption and elimination rates, and increased area under the curve (AUC0-t) when administered as part of the nanodispersion preparation (FUN) in rat plasma following oral administration.
    Karelinine
  • HY-115995
    Antitumor agent-50
    Antitumor agent-50 (compound 1a), a thiazolidinone, is a potent antitumor agent. Antitumor agent-50 has the potential for osteosarcoma (OS) research.
    Antitumor agent-50
  • HY-N17310
    Polygalaxanthone VIII
    Polygalaxanthone VIII is a natural product that can be found in Polygala tenuifolia.
    Polygalaxanthone VIII
  • HY-N19853
    Mangiferonic acid
    Mangiferonic acid is a triterpenoid found in the stems of Vatica diospyroides. Mangiferonic acid can be used for cancer research.
    Mangiferonic acid
  • HY-N13770
    Phrymarolin V
    Phrymarolin V is a natural lignan.
    Phrymarolin V
  • HY-N16468
    Riddelliine N-oxide
    Riddelliine N-oxide is a hepatotoxic agent. Riddelliine N-oxide is promising for research of liver-related diseases.
    Riddelliine N-oxide
  • HY-172748
    9β-Hydroxyhexahydrocannabinol
    9β-Hydroxyhexahydrocannabinol is a synthetic cannabinoid derivative. 9β-Hydroxyhexahydrocannabinol exhibits cytotoxicity against various tumor cell lines, such as HCT-116, MCF-7, K562, MIAPaCa-2, PANC-1, A549, PC-3 and SW-620, with IC50 values ranging from 15.23 to 33.74 μM. 9β-Hydroxyhexahydrocannabinol can be used in the study of cancer.
    9β-Hydroxyhexahydrocannabinol
  • HY-138146
    4-Dehydrowithaferin A
    4-Dehydrowithaferin A is the analogue of withaferin A. Withaferin A is a withanolide isolated from Withania somnifera. 4-Dehydrowithaferin A has the potential for the research of multiple myeloma.
    4-Dehydrowithaferin A
  • HY-131171
    3β,5α-Tetrahydronorethisterone
    3β,5α-Tetrahydronorethisterone is a tetrahydro derivative of norethindrone (NET).
    3β,5α-Tetrahydronorethisterone
  • HY-N16755
    Vaticanol A
    Vaticanol A is a natural phenolic compound.
    Vaticanol A
  • HY-172819
    Cannabigerobutolic acid methyl ester
    Cannabigerobutolic acid methyl ester is a drug derivative. Cannabigerobutolic acid methyl ester can be used in research on neurological diseases.
    Cannabigerobutolic acid methyl ester