Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W746847

Epibetulinic acid-d₃
Epibetulinic acid-d₃ is the deuterium labeled Epibetulinic acid (HY-N0223). Epibetulinic acid exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC₅₀s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity.

HY-B1115S

Buspirone-d₈ hydrochloride
Buspirone-d₈ (hydrochloride) is the deuterium labeled Buspirone hydrochloride. Buspirone hydrochloride is an anxiolytic psychotropic agent, is used to treat generalized anxiety disorder (GAD).

HY-B0451AS2

Dopamine-d₂ hydrochloride		99.6%
Dopamine-d₂ (hydrochloride) is the deuterium labeled Dopamine hydrochloride (ASL279).

HY-W014674S

(2,6-Dichlorophenyl)acetic-2,2-d₂
(2,6-Dichlorophenyl)acetic-2,2-d₂ is the deuterium labeled 2,6-Dichlorophenylacetic acid.

HY-133091S

7-Ethoxycoumarin-d₅
7-Ethoxycoumarin-d₅ is deuterium labeled 7-Ethoxycoumarin. 7-Ethoxycoumarin is a substrate for cytochrome P450(CYP450) and has been used in the functional characterization of various CYPs.

HY-D0314S

1-(2-Methoxyphenyl)azo-2-naphthol-d₃
1-(2-Methoxyphenyl)azo-2-naphthol-d₃ is the deuterium labeled 1-(2-Methoxyphenyl)azo-2-naphthol.

HY-W751180

3-Hydroxy Midostaurin-¹³C₆
3-Hydroxy Midostaurin-¹³C₆ (CGP52421-¹³C₆) is the ¹³C-labeled 3-Hydroxy Midostaurin (HY-108263). 3-Hydroxy Midostaurin (CGP 52421), a metabolite of PKC412, effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC₅₀s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively. 3-Hydroxy Midostaurin is less selective but more cytotoxic than PKC412.

HY-W011591S2

1-Bromotetradecane-d₄
1-Bromotetradecane-d₄ is the deuterium labeled 1-Bromotetradecane.

HY-W130532S

2,4,6-Trifluorbenzyl alcohol-d₂
2,4,6-Trifluorbenzyl alcohol-d₂ is the deuterium labeled 2,4,6-Trifluorbenzyl alcohol.

HY-W747167

[(R)-2-(Phenylphosphonomethoxy)propyl]adenine-d₅
[(R)-2-(Phenylphosphonomethoxy)propyl]adenine-d₅ (Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate-d₅) is the deuterium labeled Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate (HY-W004381).

HY-W742258

2-Bromo-1-(p-tolyl)ethanone-d₃
2-Bromo-1-(p-tolyl)ethanone-d₃ (Alpha-bromo-4-methylacetophenone-d₃) is the deuterium labeled 2-Bromo-1-(p-tolyl)ethanone (HY-W007335).

HY-B0508S

Ornidazole-d₅
Ornidazole-d₅ is deuterium labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease.

HY-N0322S8

Cholesterol-¹⁸O
Cholesterol-¹⁸O is the ¹⁸O-labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.

HY-W714529

Digoxigenin-d₃
Digoxigenin-d₃ (Lanadigenin-d₃) is the deuterium labeled Digoxigenin (HY-B1025). Digoxigenin (DIG) is a steroid. DIG is used for situ hybridization as a labeling molecule probe due to long shelf life and fast detection and high sensitivity of DIG-labeled riboprobes.

HY-66008S2

N-Acetyl mesalazine-¹³C₆
N-Acetyl mesalazine-¹³C₆ (N-Acetyl-5-aminosalicylic acid-¹³C₆) is a deuterated labeled N-Acetyl mesalazine (HY-66008). N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the primary intestinal metabolite of 5-Aminosalicylic Acid (HY-15027) and serves as a biomarker for evaluating the efficacy of 5-Aminosalicylic Acid (HY-15027). N-Acetyl mesalazine can scavenge free radicals, reduce DNA base hydroxylation, and ameliorate mucosal inflammation. N-Acetyl mesalazine can be used in the study of diseases such as colitis and colon cancer.

HY-A0093S1

Mexiletine-d₃ hydrochloride
Mexiletine-d₃ (hydrochloride) is deuterium labeled Mexiletine (hydrochloride). Mexiletine hydrochloride (KOE-1173 hydrochloride), a Class IB antianhythmic, is a non-selective voltage-gated sodium channel blocker[1][2].

HY-W012713S

Ac-D-Ala-OH-d₄		99.0%
Ac-D-Ala-OH-d₄ is the deuterium labeled Ac-D-Ala-OH.

HY-W016009S2

2'-Deoxyadenosine-5'-monophosphate-¹⁵N₅ dilithium
2'-Deoxyadenosine-5'-monophosphate-¹⁵N₅ dilithium is ¹⁵N labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.

HY-179814S

3-Bromo-N,N-di(methyl-¹³C)propan-1-amine oxide
3-Bromo-N,N-di(methyl-¹³C)propan-1-amine oxide is the ¹³C-labeled 3-Bromo-N,N-di(methyl-)propan-1-amine oxide.

HY-143985S

Maytansinoid DM4 impurity 5-d₆
Maytansinoid DM4 impurity 5-d₆ is the deuterium labeled Maytansinoid DM4 impurity 5.

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