Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11097)
Related Products (11097)
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Glucosylsphingosine-13C6
0 ImagesSynonyms: Glucopsychosine-13C6; Lyso-Gb1-13C6; Lyso-GL1-13C6Glucosylsphingosine-13C6 (Glucopsychosine-13C6) is the 13C-labeled Glucosylsphingosine (HY-N7745). Glucosylsphingosine (lyso-Gb1) is a deacylated form of glucosylceramide with neurotoxicity and is also a noncompetitively inhibitor of glucocerebrosidase with a Ki value of 30 μM. Glucosylsphingosine is promising for research of Krabbe and Gaucher disease.
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Doxapram-d5 hydrochloride
0 ImagesCat. No.: HY-129146SPurity: 99.0%Doxapram-d5 hydrochloride is deuterium labeled Doxapram hydrochloride. Doxapram hydrochloride is a respiratory stimulant. Doxapram hydrochloride increases breathing rate and depth by acting on the brain's respiratory centers and peripheral chemoreceptors. Doxapram hydrochloride inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50s of 410 nM, 37 μM, 9 μM, respectively. Doxapram hydrochloride inhibits the Ca²⁺-activated potassium current (IC50 ≈ 13 μM) and Ca²⁺-independent potassium current (IC50 ≈ 20 μM) in type I cells of the carotid body. Doxapram hydrochloride significantly prolongs the effective refractory period of the atrium and has an anti-arrhythmic effect. Doxapram hydrochloride can be used for the study of respiratory depression such as post-anesthesia respiratory depression, chronic obstructive pulmonary disease and apnea of prematurity.
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Zymosterol-d5
0 ImagesCat. No.: HY-114297SCAS No.: 1246298-29-2Zymosterol-d5 is deuterium labeled Zymosterol.
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Esomeprazole-d3
0 ImagesCat. No.: HY-17021S1Synonyms: (S)-Omeprazole-d3; (-)-Omeprazole-d3Esomeprazole-d3 is deuterium labeled Esomeprazole. Esomeprazole ((S)-Omeprazole) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole has the potential for symptomatic gastroesophageal reflux disease research.
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3-O-Methyl-D-glucose-13C
0 Images3-O-Methyl-D-glucose-13C is the 13C labeled 3-O-Methyl-D-glucose.
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Desoxycarbadox-d3
0 ImagesDesoxycarbadox-d3 is the deuterium labeled Desoxycarbadox. Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound.
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Puromycin-d3 dihydrochloride
0 ImagesCat. No.: HY-B1743ASPurity: 98.0%Synonyms: CL13900-d3 dihydrochloridePuromycin-d3 (dihydrochloride) is the deuterium labeled Puromycin dihydrochloride. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis.
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15(S)-HETE-d8
0 ImagesCat. No.: HY-113336SCAS No.: 84807-87-415(S)-HETE-d8 is the deuterium labeled 15(S)-HETE.
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D-Galactose-d2-1
0 ImagesCat. No.: HY-N0210S11CAS No.: 1176791-08-4Synonyms: D-(+)-Galactose-d2-1D-Galactose-d2-1 is the deuterium labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose.
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Sapienic acid-d19
0 ImagesSapienic acid-d19 is a deuterated labeled Sapienic acid. Sapienic acid is a fatty acid commonly found on the skin and in mucosa. Sapienic acid has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. Sapienic acid is active against Streptococcus sanguinis, Streptococcus mitis and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively.
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(R)-Lansoprazole-d4
0 ImagesCat. No.: HY-13662BSPurity: 99.13%Synonyms: Dexlansoprazole-d4(R)-Lansoprazole-d4 is deuterium labeled (R)-Lansoprazole. (R)-Lansoprazole is the R enantiomer of Lansoprazole, Lansoprazole (AG 1749) is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole (AG 1749) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).
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Lauryl maltose neopentyl glycol-d42
0 ImagesCat. No.: HY-138193SPurity: 99%Synonyms: LMNG-d42Lauryl maltose neopentyl glycol-d42 (LMNG-d42) is the deuterium labeled Lauryl maltose neopentyl glycol (HY-138193). Lauryl maltose neopentyl glycol (LMNG) is a detergent that can solubilize and stabilize membrane proteins. Lauryl maltose neopentyl glycol extracts integral membrane proteins from membranes, and improves substantially the stability of various membrane proteins, including G protein-coupled receptors and respiratory complexes.
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Ramelteon-d5
0 ImagesCat. No.: HY-A0014SCAS No.: 1134159-63-9Synonyms: TAK-375-d5Ramelteon-d5 is deuterium labeled Ramelteon. Ramelteon is a potent, highly selective, and orally active agonist of MT1/MT2 with Ki values of 14 and 112 pM, respectively. Ramelteon has the potential for the research of insomnia. Ramelteon consistently reduces sleep onset after long-term treatment, with no next-morning residual effects or rebound insomnia or withdrawal symptoms upon discontinuation.
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Vapendavir-d5
0 ImagesCat. No.: HY-106254SCAS No.: 2738376-73-1Synonyms: BTA798-d5Vapendavir-d5 is the deuterium labeled Vapendavir. Vapendavir (BTA798) is a potent enteroviral capsid binder (CB). Vapendavir (BTA798) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains.
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Bromhexine-d3 hydrochloride
0 ImagesCat. No.: HY-B0372ASPurity: 99.0%Bromhexine-d3 (hydrochloride) is deuterium labeled Bromhexine (hydrochloride). Bromhexine hydrochloride is a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM. Bromhexine hydrochloride can prevent and manage SARS-CoV-2 infection. Bromhexine hydrochloride is an autophagy agonist. Bromhexine hydrochloride is a mucolytic cough suppressant and has the potential for a range of respiratory conditions.
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Diclofenac-13C6 sodium
0 ImagesSynonyms: GP 45840-13C6Diclofenac-13C6 (Sodium) is the 13C6 labeled Diclofenac (Sodium). Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.
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Glycochenodeoxycholic acid 3-sulfate-d5 disodium
0 ImagesCat. No.: HY-143645SPurity: 99.33%Glycochenodeoxycholic acid 3-sulfate-d5 (disodium) is the deuterium labeled Glycochenodeoxycholic acid 3-sulfate disodium.
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Cyclosporin A acetate-d4
0 ImagesCat. No.: HY-B0579S2Synonyms: Cyclosporine A acetate-d4; Ciclosporin A acetate-d4; CsA acetate-d4Cyclosporin A acetate-d4 (Cyclosporine A acetate-d4) is the deuterated-labeled Cyclosporin A (HY-B0579). Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM. Cyclosporin A is a molecular glue, binds to cyclophilin and calcineurin, leading to inactivation of nuclear Factor of activated T Cells (NFAT) and a subsequent decrease in the immune response. Cyclosporin A also inhibits CD11a/CD18 adhesion.
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L-2-Aminobutyric acid-d3
0 ImagesCat. No.: HY-W010589SCAS No.: 929202-07-3Synonyms: H-Abu-OH-d3L-2-Aminobutyric acid-d3 is the deuterium labeled L-2-Aminobutyric acid. L-2-Aminobutyric acid is a non-proteinogenic amino acid that exists in human tissues and body fluids. L-2-Aminobutyric acid is formed by the transamination of oxobutyric acid. L-2-Aminobutyric acid can serve as a precursor for anticonvulsant and anti-tuberculosis agents and is a key intermediate in the chemical and pharmaceutical industries.
