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  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds 関連製品 (10866):

製品番号 製品名 製品効果 純度 構造式
  • HY-N2362S1
    DL-Alanine-13C-3 98.0%
    DL-Alanine-13C-3 is the 13C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver.
    DL-Alanine-<sup>13</sup>C-3
  • HY-W747676
    Glyphosate-13C 99.2%
    Glyphosate-13C is the 13C-labeled Glyphosate (HY-B0863). Glyphosate, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative of the amino acid glycine. Glyphosate inhibits the enzymatic activity of the 5-endopyruvylshikimate 3-phosphate synthase (EPSPS) in the shikimic acid pathway, preventing the synthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. Glyphosate induces oxidative stress, neuroinflammation, and mitochondrial dysfunction, processes that lead to neuronal death by autophagia, necrosis, or apoptosis, as well as the appearance of behavioral and motor disorders.
    Glyphosate-<sup>13</sup>C
  • HY-W754151
    N-Desmethyl apalutamide-d4 99.63%
    N-Desmethyl apalutamide-d4 is the deuterium-labeled N-Desmethyl-Apalutamide (HY-135331). N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration.
    N-Desmethyl apalutamide-d<sub>4</sub>
  • HY-159002S
    Methyl-warfarin-d3 99.95%
    Methyl-warfarin-d3 is a deuterated labeling methylated Warfarin (HY-B0687).
    Methyl-warfarin-d<sub>3</sub>
  • HY-131105S
    Cimbuterol-d9 99.13%
    Cimbuterol-d9 is the deuterium labeled Cimbuterol (HY-131105). Cimbuterol is a β-adrenergic agonist. β-adrenergic agonists act as bronchodilators and tocolytics. β-adrenergic agonists promote growth.
    Cimbuterol-d<sub>9</sub>
  • HY-B0261S2
    Meloxicam-13C,d3 ≥99.90%
    Meloxicam-13C,d3 is deuterium labeled Meloxicam. Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively.
    Meloxicam-<sup>13</sup>C,d<sub>3</sub>
  • HY-139003S
    4'-Hydroxywarfarin-d4
    4'-Hydroxywarfarin-d4 is the deuterium labeled 4′-Hydroxywarfarin.
    4'-Hydroxywarfarin-d<sub>4</sub>
  • HY-13585S
    Carmustine-d8 98.34%
    Carmustine-d8 is the deuterium labeled Carmustine. Carmustine is an antitumor chemotherapeutic agent, which works by akylating DNA and RNA.
    Carmustine-d<sub>8</sub>
  • HY-139951S
    3-Hydroxy-3-methylglutaryl-Coenzyme A-d3 ammonium
    3-Hydroxy-3-methylglutaryl-Coenzyme A-d3 (ammonium) is the deuterium labeled 3-Hydroxy-3-methylglutaryl-Coenzyme A ammonium.
    3-Hydroxy-3-methylglutaryl-Coenzyme A-d<sub>3</sub> ammonium
  • HY-12752S
    Alimemazine-d6 99.55%
    Alimemazine-d6 is deuterium labeled Alimemazine, which is an antihistamine.
    Alimemazine-d<sub>6</sub>
  • HY-101399S
    γ-Glu-(Phe-13C9,15N)
    γ-Glu-(Phe-13C9,15N) is the 13C and 15N labeled isotope of γ-Glu-Phe(HY-101399).γ-Glu-Phe or the postenzymatic reaction mixture enhanced the umami intensity of commercial soy sauce and model chicken soup.
    γ-Glu-(Phe-<sup>13</sup>C<sub>9</sub>,<sup>15</sup>N)
  • HY-W012480S1
    DL-Tryptophan-d8 99.64%
    DL-Tryptophan-d8 is the deuterium labeled DL-Tryptophan. DL-Tryptophan is an endogenous metabolite.
    DL-Tryptophan-d<sub>8</sub>
  • HY-A0132S10
    N-Acetyl-D-glucosamine-13C2,15N
    N-Acetyl-D-glucosamine-13C2,15N is the 13C and 15N labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc.
    N-Acetyl-D-glucosamine-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N
  • HY-W740245
    Arecaidine-d5 hydrobromide 98.52%
    Arecaidine-d5 hydrobromide is the deuterium labeled Arecaidine hydrobromide (HY-N2368B). Arecaidine hydrobromide, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrobromide is a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake.
    Arecaidine-d<sub>5</sub> hydrobromide
  • HY-N0384S1
    Homovanillic acid-d2 99.51%
    Homovanillic acid-d2 (Vanilacetic acid-d2) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.
    Homovanillic acid-d<sub>2</sub>
  • HY-115702S
    1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine-d4 ≥99.0%
    1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine-d4 ((Rac)-PAF (C16)-d4) is the deuterium labeled 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine is an endogenous inflammatory lipid mediator. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine acts as a high-affinity agonist for PAFR (GPCR), inducing platelet aggregation, vascular permeability, and leukocyte chemotaxis at extremely low concentrations. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine exerts its effects via cell surface receptors to regulate inflammation.
    1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine-d<sub>4</sub>
  • HY-14779S
    Riociguat-13C,d6 99.0%
    Riociguat-13C,d6 is the 13C and deuterium labeled Riociguat (HY-14779). Riociguat is an oral stimulator of soluble guanylate cyclase (sGC) used in the treatment of pulmonary hypertension.
    Riociguat-<sup>13</sup>C,d<sub>6</sub>
  • HY-W748961
    Norethindrone Acetate-2,2,4,6,6,10-d6
    Norethindrone Acetate-2,2,4,6,6,10-d6 is deuterated labeled Norethindrone Acetate-2,2,4,6,6,10.
    Norethindrone Acetate-2,2,4,6,6,10-d<sub>6</sub>
  • HY-W750777
    Flupyradifurone-d5 99.9%
    Flupyradifurone-d5 is the deuterium labeled Flupyradifurone (HY-145295). Flupyradifurone is a systemic?nAChR?agonist that interferes with signal transduction in the central nervous system of sucking pests. Flupyradifurone can be used as a butenolide?insecticide.
    Flupyradifurone-d<sub>5</sub>
  • HY-N2086S
    Ethyl palmitate-d31 98.0%
    Ethyl palmitate-d31 is the deuterium labeled Ethyl palmitate. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent.
    Ethyl palmitate-d<sub>31</sub>