Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11097)
Related Products (11097)
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Cholestenone-13C2
0 ImagesSynonyms: 4-Cholesten-3-one-13C2Cholestenone-13C2 is the 13C labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells.
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Clindamycin-13C,d3
0 ImagesClindamycin-13C,d3 is the 13C- and deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria.
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1-Eicosanol-d41
0 ImagesSynonyms: Arachidyl alcohol-d411-Eicosanol-d41 (Arachidyl alcohol-d41) is the deuterium labeled 1-Eicosanol (HY-W004263). 1-Eicosanol is a natural compound with antioxidant activity found in Justicia insularis leaves. 1-Eicosanol can be used as an antioxidant.
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Sodium 2-oxobutanoate-13C4
0 ImagesSodium 2-oxobutanoate-13C4 is the 13C labeled Sodium 2-oxobutanoate.
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Isradipine-d3
0 ImagesCat. No.: HY-B0233SCAS No.: 1189959-59-8Isradipine-d3 (PN 200-110-d3) is the deuterium labeled Isradipine. Isradipine (PN 200-110) is an orally active L-type calcium channel blocker. Isradipine, as a powerful peripheral vasodilator, is a dihydropyridine calcium antagonist with selective actions on the heart as well as the peripheral circulation. Isradipine is a potentially viable neuroprotective agent for Parkinson's disease.
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Sodium butyrate-d3
0 ImagesSynonyms: Butanoic acid-d3 sodium; Butyric acid-d3 sodiumSodium butyrate-d3 (Butanoic acid-d3 sodium) is the deuterium labeled Sodium butyrate (HY-B0350A). Sodium Butyrate (sodium butanoate) is an inhibitor of HDAC, possessing anti-tumor activity.
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Octrizole-13C6
0 ImagesCat. No.: HY-W770434Synonyms: UV-329-13C6Octrizole-13C6 is 13C labeled Octrizole.
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Clencyclohexerol-d10
0 ImagesClencyclohexerol-d10 is the deuterium-labeled Clencyclohexerol (HY-117406). Clencyclohexerol-d10 is a β-agonist. Clencyclohexerol-d10 can be used as a growth promoter in animals.
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5α-Cholestane-d6
0 Images5α-Cholestane-d6 is the deuterated-labeled 5α-Cholestane (HY-133970). 5α-Cholestane is a steroidal hydrocarbon and fecal stanol, and is used as an internal standard for gas chromatographic sterol analysis. 5α-Cholestane is the parent steroidal skeleton of polyhydroxylated brassinosteroids of plant origin. It is used as an internal standard for GC-FID and GC-MS analysis of fecal sterols in urine and sludge samples. 5α-Cholestane can be used in studies of age- or disease-related skeletal muscle atrophy.
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Deupirfenidone-d3
0 ImagesSynonyms: LYT-100; AMR69-d3Deupirfenidone-d3 is the deuterium labeled Pirfenidone (HY-B0673). Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities.
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Cabotegravir-d5
0 ImagesSynonyms: GSK-1265744-d5; S/GSK1265744-d5Cabotegravir-d5 is deuterium labeled Cabotegravir.
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Sotorasib-d7 isomer
0 ImagesCat. No.: HY-114277BSSynonyms: AMG-510-d7 isomerSotorasib-d7 isomer (AMG-510-d7 isomer) is the deuterium labeled Sotorasib isomer.
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(rac)-N,O-Didesmethyl Tramadol-d3
0 ImagesCat. No.: HY-132417SCAS No.: 1261398-22-4(rac)-N,O-Didesmethyl Tramadol-d3 is a deuterium labeled (rac)-N,O-Didesmethyl Tramadol. (rac)-N,O-Didesmethyl Tramadol is the main metabolite of Tramadol.
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2-Oxoacetic acid hydrate-13C2
0 ImagesSynonyms: Glyoxylic Acid monohydrate-13C22-Oxoacetic acid hydrate-13C2 (Glyoxylic Acid monohydrate-13C2) is the 13C-labeled 2-Oxoacetic acid hydrate (HY-W047499).
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Melamine-15N3,13C3
0 ImagesCat. No.: HY-Y1117S2CAS No.: 1246816-14-7
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Cefoperazone-d5
0 ImagesCefoperazone-d5 is deuterium labeled Cefoperazone. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity.
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dGTP-d14 dilithium
0 ImagesCat. No.: HY-138616S1Purity: 98.5%Synonyms: 2'-Deoxyguanosine-5'-triphosphate-d14 dilithiumdGTP-d14 (2'-Deoxyguanosine-5'-triphosphate-d14) dilithium is deuterium labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
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Glycodeoxycholic acid-d6
0 ImagesGlycodeoxycholic acid-d6 is the deuterium labeled Glycodeoxycholic Acid. Glycodeoxycholic Acid is an endogenous metabolite.
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FL118-C3-O-C-amide-C-NH2-d5
0 ImagesCat. No.: HY-161022SFL118-C3-O-C-amide-C-NH2-d5 is a deuterium labeled FL118-C3-O-C-amide-C-NH2.
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Guanosine triphosphate-15N5,d14 dilithium
0 ImagesCat. No.: HY-113225S4Purity: 98.4%Synonyms: GTP-15N5,d14 dilithiumGuanosine triphosphate-15N5,d14 dilithium (GTP-15N5,d14 dilithium) is the deuterated, 15N-labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate (GTP) is a critical nucleotide and regulator of cellular metabolism. Guanosine triphosphate promotes ribosomal DNA localization, pre-rRNA transcription and ribosome biogenesis by binding to RNA polymerase I and GPN proteins (GPN1/3). Guanosine triphosphate links MYC-dependent ribosome biogenesis to nucleotide sufficiency, acts as a metabolic gatekeeper supporting protein synthesis, DNA/RNA synthesis and cellular signal transduction, while also participating in the physiological activities of pancreatic β-cells and serving as an oxidative substrate for reactive oxygen species. In small cell lung cancer with high MYC expression, Guanosine triphosphate accumulates through the IMPDH-driven synthetic pathway, thereby affecting apoptosis and mitotic processes. Guanosine triphosphate is used in the research of small cell lung cancer, hepatoblastoma and cellular metabolism.
